Photo Rounds

Erythematous axillary plaques

A 67-year-old woman presented to the Family Medicine Skin Clinic for evaluation of bilateral axillary lesions that appeared 4 months earlier. The patient reported no changes in deodorants or detergents and said that the rash would wax and wane slightly, but it never resolved. She noted that application of an over-the-counter antifungal cream and powder caused an increase in inflammation. A scraping of the scale for a potassium hydroxide (KOH) preparation test was negative for fungal elements.

What’s your diagnosis?


 

References

Erythematous axillary plaques

Due to the condition’s persistence and the negative KOH prep, erythrasma was the most likely diagnosis.

Erythrasma is caused by a bacterial infection with Corynebacterium minutissimum. It occurs in intertriginous areas that tend to be moist and irritated by friction. The erythema is usually a dull red, rather than the bright red that one would see with yeast infections. In addition, there is typically central pallor.

Woods lamp examination can confirm the diagnosis by showing coral pink fluorescence. In this patient, however, there was no fluorescence because the patient had recently washed the area and, thus, removed the porphyrins produced by C minutissimum. Biopsy for pathology is not usually necessary.

Erythrasma is treated with topical clindamycin, fusidic acid, or mupirocin. Oral macrolides and tetracyclines are also effective.1 Due to the chronicity of the erythrasma and the discomfort it caused, this patient opted for oral doxycycline 100 mg twice daily for 10 days. At follow-up 2 weeks later, the erythrasma had resolved.

Photo and text courtesy of Daniel Stulberg, MD, FAAFP, Department of Family and Community Medicine, University of New Mexico School of Medicine, Albuquerque

Recommended Reading

A woman with scaling, and painful, crusted, erythematous papules and pustules on her face
MDedge Family Medicine
Painful ingrown nail
MDedge Family Medicine
Lower SARS-CoV-2 vaccine responses seen in patients with immune-mediated inflammatory diseases
MDedge Family Medicine
Scaly patches on hand and feet
MDedge Family Medicine
How early can laser treatment for port wine stains in infants be initiated?
MDedge Family Medicine
Benzene found in some sunscreen products, online pharmacy says
MDedge Family Medicine
FDA approves secukinumab in psoriasis patients age six and older
MDedge Family Medicine
Asymptomatic hyperpigmented skin changes
MDedge Family Medicine
Intravenous immunoglobulin controls dermatomyositis in phase 3 trial
MDedge Family Medicine
GRAPPA refines recommendations on psoriatic disease treatment
MDedge Family Medicine