Clinical Edge Journal Scan

Atopic dermatitis: Inadequate disease control and QoL impairments among patients receiving topical therapy


 

Key clinical point: Almost a fifth of patients with atopic dermatitis (AD) receiving topical therapy had an uncontrolled disease and reported impairment in work productivity along with a lower quality of life (QoL).

Major finding: Overall, physicians identified 24.5% of patients as having uncontrolled disease. Patients with uncontrolled vs controlled disease had higher impairment in QoL (Dermatology Life Quality Index, 8.8 vs 6.0; P = .0003) and work productivity (Work Productivity and Activity Impairment, 23.5 vs 16.2; P = .0488).

Study details: Findings are from a retrospective, point-in-time study including 394 adults and 144 adolescent patients with moderate-to-severe AD who received topical therapy for at least 1 month.

Disclosures: This study was funded by Incyte Corporation. JH Lofland and VN Joish declared being employees and shareholders of Incyte Corporation. Three of the other authors declared being employees of Adelphi Real World.

Source: Anderson P et al. Dermatol Ther (Heidelb). 2021 Jul 15. doi: 10.1007/s13555-021-00580-2 .

Recommended Reading

Use of Complementary Alternative Medicine and Supplementation for Skin Disease
MDedge Dermatology
Upadacitinib shows superior efficacy over dupilumab for moderate-to-severe atopic dermatitis in phase 3b
MDedge Dermatology
Difamilast ointment shows promise for pediatric atopic dermatitis in phase 3
MDedge Dermatology
Cold atmospheric plasma alleviates AD severity without any safety issues
MDedge Dermatology
Sleep disturbance and geriatric age in atopic dermatitis: Is there a link?
MDedge Dermatology
Methylation on golli-MBP locus serves as an indicator of atopic dermatitis severity in children
MDedge Dermatology
Comorbidities account for higher incidence of hospitalization in patients with AD
MDedge Dermatology
Atopic dermatitis tied to increased risk for hypertension
MDedge Dermatology
Abrocitinib emerges as a potential treatment option for moderate-to-severe atopic dermatitis
MDedge Dermatology
Atopic dermatitis: Rapid improvement in skin pain with baricitinib
MDedge Dermatology