Key clinical point: The risk for preterm birth (PTB) was higher among women who underwent preconception myomectomy to treat uterine fibroids vs women with fibroids who did not undergo prior myomectomy.
Major finding: Women who underwent prior myomectomy vs those who did not were more likely to experience PTB at less than 37 weeks’ gestation (35% vs 21%; P = .02) and deliver a mean 1.4 weeks earlier (36.3±3.6 vs 37.7±3.7 weeks’ gestation; P = .02).
Study details: Findings are from a retrospective cohort study including 290 women with a viable intrauterine pregnancy, of which 70 had a prior myomectomy and the remaining 220 who did not undergo myomectomy and had at least 1 fibroid of size 5 cm or more detected at less than 21 weeks’ gestation.
Disclosures: This study was funded by the National Institute of Child Health and Human Development. The authors reported no conflict of interests.
Source: Mahalingam M et al. J Matern Fetal Neonatal Med. 2021 Oct 6. doi: 10.1080/14767058.2021.1984424 .