Clinical Edge Journal Scan

Prevalence and risk factors for ocular surface disease in patients with atopic dermatitis


 

Key clinical point: Ocular surface diseases (OSD), particularly conjunctivitis, are prevalent among patients with atopic dermatitis (AD), with the prevalence increasing with AD severity and childhood onset of AD.

Major finding: Of all OSDs, lifetime prevalence was highest for conjunctivitis (66.6%), followed by other OSDs, such as hordeolum (63.5%), blepharitis (11%), and keratitis (9.7%). The lifetime occurrence of conjunctivitis was higher for mild (adjusted odds ratio [aOR] 1.48; 95% CI 1.02-2.14), moderate (aOR 1.73; 95% CI 1.19-2.53), and severe (aOR 2.17; 95% CI 1.42-3.21) AD vs. inactive AD and for childhood-onset vs. adult-onset AD (aOR 1.34; 95% CI 1.16-1.56).

Study details: Findings are from a nationwide, cross-sectional questionnaire-based survey sent to 16,718 patients with AD, of which 7,044 patients responded.

Disclosures: This study was funded by the Kgl. Hofbundtmager Aage Bang Foundation. The authors declared serving as advisory board members, investigators, and consultants or receiving honoraria, grants, and funding from several sources.

Source: RΓΈnnstad ATM et al. J Eur Acad Dermatol Venereol. 2021 (Nov 23). Doi: 10.1111/jdv.17832.

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