Clinical Edge Journal Scan

Effect of burdensome symptoms on treatment preferences of patients with PsA


 

Key clinical point: Patients with psoriatic arthritis (PsA) reported musculoskeletal pain as the most burdensome symptom and preferred a treatment regimen that improved their joint symptoms and did not include a methotrexate coprescription.

Major finding: J oint pain (98%), fatigue (94%), and morning stiffness (94%) were the most common symptoms of PsA; therefore, 74% of patients preferred therapies that improved joint-related vs. psoriasis-related symptoms, with once-daily oral medication being preferred by 38% of patients and 47% of patients with experience receiving methotrexate preferring a treatment regimen without methotrexate.

Study details: This cross-sectional, web-based survey included 332 adults from ArthritisPower who had a self-reported physician diagnosis of PsA.

Disclosures: This study was funded by AbbVie and RTI Health Solutions. Three authors declared being employees of RTI Health Solutions, two authors declared being employees or share/stockowners of AbbVie, and other authors declared financial/nonfinancial ties with various sources.

Source: Ogdie A et al. Experiences and treatment preferences in patients with psoriatic arthritis: A cross-sectional study in the ArthritisPower registry. Rheumatol Ther. 2022 (Mar 13). Doi: 10.1007/s40744-022-00436-x

Recommended Reading

Trial gives new guidance for choosing initial PsA treatment
MDedge Rheumatology
Introducing adalimumab vs. escalating methotrexate in patients with inadequately controlled PsA
MDedge Rheumatology
PsA: Methotrexate+leflunomide more effective but less well tolerated than methotrexate monotherapy
MDedge Rheumatology
PsA: Comparable efficacy, safety, and persistence with TNFi or ustekinumab in real world
MDedge Rheumatology
Reduced humoral response to SARS-CoV-2 vaccine in patients receiving systemic therapy for PsA
MDedge Rheumatology
Scoring by MRI is an effective way to identify change in clinical outcomes of PsA
MDedge Rheumatology
PsA: Deucravacitinib shows promise in phase 2
MDedge Rheumatology
Degree of disease control influences abnormalities in renal parameters in PsA
MDedge Rheumatology
Degree of disease control influences abnormalities in renal parameters in PsA
MDedge Rheumatology
Secukinumab shows a satisfactory retention rate in PsA in real-world setting
MDedge Rheumatology