Minocycline-Induced Pigmentation Mimicking Persistent Ecchymosis
This article has been peer reviewed and approved by Ranon Ephraim Mann, MD, Assistant Professor, Department of Medicine (Dermatology), Albert Einstein College of Medicine. Review date: June 2009.
Drs. Youssef and Young report no conflict of interest. Dr. Langevin is a consultant for Neutrogena Corporation. This relationship is not relevant to this article. The authors report no discussion of off-label use. Dr. Mann reports no conflict of interest. The staff of CCME of Albert Einstein College of Medicine and Cutis® have no conflicts of interest with commercial interest related directly or indirectly to this educational activity. Dr. Youssef was a medical student, George Washington School of Medicine and Health Sciences, Washington, DC. She currently is an intern, University of Wisconsin, Madison. Dr. Langevin is Clinical Instructor and Dr. Young is Asscoiate Clinical Professor of Medicine and Cochief of Clinical Services in Dermatology, both from the University of California, Los Angeles.
Sherry Youssef, MD, MPH, MS; Kathy Kim Langevin, MD, MPH; Lorraine C. Young, MD
We report an unusual case of minocycline-induced pigmentation mimicking persistent ecchymosis in a patient with persistent (20 months' duration) bluish black discoloration of the medial and lateral aspects of the left ankle following an avulsion fracture. We review the common presentations of minocycline-induced pigmentation as well as some of the more unusual presentations.