Evidence-Based Reviews

Late-life depression: Focused IPT eases loss and role changes

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The ‘sick role.’ The therapist assigned Mrs. E the “sick role” to emphasize that major depression can be a severe illness. A therapist might say: “If you had pneumonia, you wouldn’t think of trying to rake leaves. You would rest and take care of yourself to speed the healing. Persons with major depression should do the same.”

The contract. The therapist also explained to Mrs. E that contracting to meet weekly for 12 to 16 weeks is part of the treatment. A contract:

  • encourages patients to commit to an IPT trial for a reasonable time
  • presses patients to achieve adequate progress by the deadline
  • discourages digression, avoidance of painful subjects, and dependence on the therapist.
IPT’s framework. IPT sees clinical depression as having three components: a symptom function, social and interpersonal relations, and personality and character problems (Table 1).5,6 Because IPT is brief, its interventions focus on the first two components. The third may be addressed indirectly, such as when a patient with a depressogenic personality style learns new social skills, compensates better, and improves his or her symptoms.

IPT begins with a complete psychiatric evaluation, including the patient’s past, family, and social histories; alcohol and drug use; medical comorbidities; mental status exam; and sometimes blood screening to rule out metabolic abnormalities. Antidepressants are prescribed as needed to relieve vegetative symptoms and are used during IPT when indicated.

Interpersonal inventory. Each of the patient’s interpersonal relationships is then systematically reviewed. This inventory sets the stage for exploring relationships that may be linked to the depressive symptoms or offer opportunities for trying alternate coping trategies, such as learning to seek social support (Table 2).

Table 1

IPT’s understanding of depression comprises 3 component processes

ComponentDescription
Symptom functionBiological or psychological causes may trigger neurovegetative signs and symptoms
Interpersonal and social relationsInfluenced by childhood learning, social reinforcement, personal mastery, and competence
Personality and character problemsEnduring traits such as excess anger, guilt, impaired communication, or low self-esteem may impair patient’s ability to maintain satisfying interpersonal relationships
Source: References 5 and 6
Table 2

‘How-to’ checklist of IPT procedures

  • Complete thorough biopsychosocial evaluation
  • Diagnose depression
  • Provide psychoeducation
  • Assign patient the ‘sick role’
  • Determine if antidepressant medication is indicated
  • Explore ‘interpersonal inventory’ in detail
  • Relate depressive symptoms to an interpersonal context in ‘here and now’
  • Establish treatment contract (12 to 16 weekly sessions)
  • Establish IPT focus or problem area
  • Use specific interventions for each IPT focus
  • Regularly view depressive symptoms and progress toward change
  • Terminate treatment as per IPT contract, while teaching techniques to help patient cope independently after IPT

IPT’S FOUR FOCI

IPT’s goal is to relieve depressive symptoms by identifying and focusing on problems that may have caused or are perpetuating those symptoms. Most of the reasons depressed patients give for seeking help fall into four foci: unresolved grief, role transition, role dispute, and interpersonal deficit (Table 3).5,6 The therapist uses clarification, interpretation, confrontation, and testing of perceptions and performance to address each focus, as detailed in the IPT manual.6

The therapist acts as the patient’s advocate, and focuses treatment on interpersonal relationships in the “here and now,” not past traumas, childhood conflicts, cognitive-behavioral interventions, or intrapsychic themes. No attempt is made to restructure personality.

Progress in relieving depressive symptoms is reviewed regularly, and treatment ends within the contract’s time limits in many cases. Older patients may need additional sessions because they often take longer to respond to antidepressant trials (6 to 8 weeks, compared with 3 to 4 weeks for younger adults). We allow older patients to “catch up” with additional sessions if illness, lack of transportation, or other problems prevent them from receiving the “full dose” of IPT.

IPT does not work for all patients. Consider other types of treatment if a patient shows no discernable benefit.

Table 3

IPT’s 4 foci, specific to late-life depression

FocusDescription
Unresolved griefEmotional reactions to the death of another person (not the loss of a job or one’s health)
Role transitionDifficulty adjusting to life change (such as retirement, ceasing to drive, or moving to an apartment)
Role disputeNonreciprocal expectations between two or more persons that predispose or perpetuate depressive symptoms
Interpersonal deficitHistory of social impoverishment or inadequate or nonsustaining interpersonal relationships
Source: References 5 and 6

Case continued: stalled in grief

As the weeks pass, Mrs. E improves but remains hypoactive and reclusive. She seems afraid to take any action without her late husband’s approval. Thinking about making independent decisions overwhelms her, and she withdraws to her couch to hide.

Her therapist discerns that Mrs. E needs more-active confrontation to accept that her new life requires her to make choices, even though decision-making is difficult for her. They develop a game, hronicling all decisions Mrs. E has made for the first time, such as calling a repairman and planting the summer vegetable garden by herself.

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