Evidence-Based Reviews

Antipsychotics for patients without psychosis?

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References

Others. Anger and hostility improved more with aripiprazole, 15 mg/d, than with placebo in an 8-week double-blind study of patients with borderline personality disorder.46 Quetiapine, risperidone, ziprasidone, and clozapine have shown efficacy in open-label studies and case reports.

Related resources

  • Boos J. Off label use–label off use? Ann Oncol 2003;14(1):1-5.
  • Blum RS. Legal considerations in off-label medication prescribing. Arch Intern Med 2002;162(15):1777-9.
  • Jeste DV, Dolder CR. Treatment of non-schizophrenic disorders: focus on atypical antipsychotics. J Psychiatr Res 2004;38(1):73-103.
  • Food and Drug Administration. Searchable catalog of FDA-approved drug products. www.accessdata.fda.gov/scripts/cder/drugsatfda.
Drug brand names
  • Aripiprazole • Abilify
  • Chlorpromazine • Thorazine
  • Citalopram • Celexa
  • Clozapine • Clozaril
  • Divalproex • Depakote
  • Fluoxetine • Prozac
  • Haloperidol • Haldol
  • Nortriptyline • Pamelor, Aventyl
  • Olanzapine • Zyprexa
  • Olanzapine/fluoxetine • Symbyax
  • Paroxetine • Paxil
  • Quetiapine • Seroquel
  • Risperidone • Risperdal
  • Thioridazine • Mellaril
  • Ziprasidone • Geodon
Disclosures

Dr. Trémeau receives grant/research support from Eli Lilly and Company.

Dr. Citrome receives grant/research support from AstraZeneca, Barr Laboratories, Bristol-Myers Squibb, Eli Lilly and Company, Janssen Research Foundation, and Pfizer; is a consultant to Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, Jazz Pharmaceuticals, and GlaxoSmithKline; and is a speaker for Abbott Laboratories, AstraZeneca, Eli Lilly and Company, and Pfizer.

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