SIRS: Schizophrenia International Research Society Congress
Held every two years 15th International Congress on Schizophrenia Research
Conference Coverage
High antipsychotic switch rates suggest ‘suboptimal’ prescribing for first-episode psychosis
Researchers found the most common first treatment switch, in 17.9% of patients, was from olanzapine to aripiprazole.
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New combination med for severe mental illness tied to less weight gain
Results of a 12-week study showed a significant difference in percent change in body weight from baseline between two treatment groups.
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‘Fragmented’ speech patterns may predict psychosis relapse
New research suggests that “semantic speech networks can enable deeper phenotyping of formal thought disorder and psychosis.”
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Novel long-acting injection cuts schizophrenia relapse
Monthly injections were associated with a fivefold prolongation of time to impending relapse in comparison with placebo.
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A new target in schizophrenia treatment: Brain gamma oscillations
Many previous trials in this area have failed, but it may be important to study patients relatively early in their disease course.
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Blood biomarker a ‘promising’ predictor of psychosis relapse
Copeptin has been shown previously to be a predictor of outcomes in somatic diseases.
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Nonpharma approach a potential ‘game changer’ in schizophrenia?
“We hope that this systematic review could help clinicians understand how to make cognitive remediation even more effective and even more...
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Potential first-in-class schizophrenia drug cuts negative symptoms
The results “provide further confirmation of the effectiveness of SEP-363856 in treating schizophrenia,” said Dr. Kenneth Koblan.
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Aerobic exercise may up brain-training benefits in schizophrenia
"Aerobic exercise showed a dose-response relationship to cognitive improvement," the researchers reported.
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Family environment important in early psychosis outcomes
“Having family involvement in care is one of the most robust predictors that young people with psychosis will remain engaged in mental health...
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Community programs improve psychosis outcomes
In one study, the team was able to nearly halve the time from diagnosis to initiation of antipsychotic treatment.
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Potential new biomarker for psychosis severity
The results "highlight ACE as a promising peripheral biomarker to identify patients at risk of treatment resistance to antipsychotics," the...
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Injectable vs. oral antipsychotics: Which do patients prefer?
The highest preference for LAIs was in Europe, at 88%, versus 59.1% in the United States and 70.7% in the rest of the world.
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What’s pushing cannabis use in first-episode psychosis?
It might be beneficial to identify the specific cause of the psychological discomfort driving cannabis use, such as depression, said Dr. Edoardo...
Conference Coverage
More data point to potency of genes in development of psychosis
ORLANDO – A genetic profile that’s considered risky for psychosis matters more for patients who come from an environmental background that is...