Geriatrics
FDA/CDC
FDA approves second antiamyloid for Alzheimer’s disease
Like its controversial cousin aducanumab, lecanemab was approved under the FDA’s accelerated approval pathway.
From the Journals
IV ketamine a promising option for resistant depression in older adults
Nearly 50% of participants responded to ketamine and 25% achieved complete remission from TRD.
News from the FDA/CDC
Alzheimer’s Association to CMS: Ditch restraints on amyloid drugs
The CMS coverage restrictions for anti-amyloid drugs were finalized in April on the...
From the Journals
Greater handgrip strength tied to lower risk for depression
Being physically strong may serve as a preventive factor for depression in older adults, but this is limited to specific maximum thresholds.
Conference Coverage
Antipsychotic shows benefit for Alzheimer’s agitation
Currently, there’s no Food and Drug Administration–approved treatment for agitation in AD.
Conference Coverage
SSRI tied to improved cognition in comorbid depression, dementia
Evidence suggests the drug’s receptor targets “have the potential to modulate neurotransmitter systems that are essential for regulation of...
From the Journals
Confirmed: Amyloid, tau levels rise years before Alzheimer’s onset
A new study builds on previous research by examining changes in cerebrospinal fluid biomarkers over longer periods than had been done previously...
Evidence-Based Reviews
Resilience and mind-body interventions in late-life depression
THIRD OF 4 PARTS
Enhancing resilience can improve outcomes in patients with late-life depression.
From the Journals
Nutrition for cognition: A missed opportunity in U.S. seniors?
Those who didn’t use the SNAP program experienced 2 more years of cognitive aging compared with program users.
From the Journals
Novel drug eases Parkinson’s-related constipation in early trial
The drug, ENT-01, targets abnormal clumps of alpha-synuclein that are a hallmark of Parkinson’s disease.
Opinion
How can I keep from losing my mind?
“To date the actual therapies for dementia have been disappointing.”