Gout
Conference Coverage
Investigational uricase-based gout drug meets primary endpoints in phase 3 trials
Two phase 3 trials of the once-monthly SEL-212 in refractory gout achieved and maintained serum uric acid < 6 mg/dL for ≥ 80% of the final...
Conference Coverage
URAT1 inhibitor shows ‘substantial’ uric acid reduction in phase 2 gout trial
The investigational drug, AR882, reduced serum uric acid to levels seen in people without hyperuricemia and gout.
From the Journals
Colchicine’s 2010 price spike had major impact on gout care
Colchicine prescriptions dropped sharply and patient visits for gout-related symptoms increased significantly after a 2010 U.S. Food and Drug...
Conference Coverage
Care for patients with gout needs improvement, says doctor
Failure to understand the gout disease process and goals of urate-lowering therapy (ULT) is a key barrier to achieving optimal gout therapy.
From the Journals
In families with gout, obesity and alcohol add to personal risk
Genetic makeup is the key driver for the increased risk of gout found in families with a history of the disease. This risk is increased in people...
Feature
Teamwork guides cardio-rheumatology clinics that care for unique patient population
Cardio-rheumatology programs are “the newest child” in a series of cardiology offshoots focusing on different populations, and such clinics aim to...
Feature
Phil Robinson: Rheumatologist, colleague, huntsman spider rescuer
Philip (“Phil”) Robinson, rheumatologist and associate professor at the University of Queensland and leader of global effort to understand COVID-...
From the Journals
Metabolic syndrome may promote gout in young men
Population-based studies suggest that managing metabolic syndrome may help to prevent gout in younger adults.
Conference Coverage
Intensive gout treatment meets urate goal, lowers tophi burden
A randomized trial of therapy to intensively lower urate for patients with gout showed benefits in meeting serum urate goal, tophus size, and...
Conference Coverage
Prednisone, colchicine equivalent in efficacy for CPP crystal arthritis
In an open-label, randomized trial, one in five patients on colchicine had diarrhea, tipping the safety scales in favor of prednisone.
Conference Coverage
Gout too often treated only in emergency department
A study based on patients seen at an academic medical center reinforces the need for greater attention to gout during primary care visits.