Osteoporosis
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Vitamin D insufficiency corrected with 800 IU/day
Major finding: Supplementation with 800 IU/day of vitamin D3 corrected vitamin D insufficiency in 98% of postmenopausal white women after 1 year...
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Abdominal, thoracic CT scans reliably detect incidental low lumbar BMD
Major Finding: Conventional abdominal and CT scans performed for various indications were more accurate than DXA at assessing lumbar BMD and...
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Loss of BMD linked to knee OA progression
Major finding: BMD loss of 0.1 g/cm2 was associated with a 1.25% per year loss of cartilage volume.Data source: An observational cohort study of...
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Hydrogel repaired joint defects, sped healing
Major Finding: After 6 months, joint defects treated with microfracture plus a photo-polymerized hydrogel were 86% filled, compared with a 64%...
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Osteoporosis, Vertebral Fractures May Flag Heart Risk in RA
Major Finding: Of 603 patients from a convenience sample of adults who met 1987 ACR criteria for RA classification, 230 had at least one...
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Vitamin D Assays Flawed, but Improving
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New Assay Simultaneously Measures Vitamin D Metabolites
Major Finding: The limit of detection in the assay for 24,25(OH)2D3 was 0.08 ng/mL; the limit for 24,25(OH)2D2 was 0.5 ng/mL.Data Source: Data are...
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Odanacatib Adds Bone in Alendronate-Pretreated Osteoporosis
Major Finding: The change from baseline in femoral neck bone mineral density at 2 years was +1.73% with odanacatib vs. –0.94% for placebo (P less...
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Zoledronic acid cuts vertebral fracture risk 67% in men with osteoporosis
Major Finding: Of the men receiving zoledronic acid, 1.6% developed new vertebral fractures during 2-year follow-up, compared with 4.9% of those...
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Hip Fracture Risk Rises as Elderly Start Antihypertensives
Major Finding: The risk of hip fracture within 45 days of starting an antihypertensive drug increased by 43% in elderly patients (incidence rate...