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THA Patient-Reported Outcomes Differ by Underlying Diagnosis

In the September 24th BMC Medicine, Jasvinder A. Singh and David G. Lewallen, reported that patients with osteoarthritis and avascular necrosis have better functional outcomes than patients with rheumatoid arthritis after undergoing primary total hip arthroplasty (THA); patients with avascular necrosis have worse pain outcomes.

“This study was conducted to assess whether patient-reported outcomes differ by the underlying diagnosis … in patients undergoing primary total hip arthroplasty,” the study authors explained. The underlying diagnoses included rheumatoid arthritis, inflammatory arthritis, osteoarthritis, and avascular necrosis of the bone.

The authors prospectively collected data, including moderate-severe activity limitation and moderate-severe pain two- and five-years after primary THA. Overall, 5707 and 3289 THAs at 2-years and 5-years, respectively were included; 50% of the patients were women and the mean age was 65 years. Three percent of the patients had an underlying diagnosis of rheumatoid arthritis, 87% osteoarthritis, 7% avascular necrosis of bone, and 3% other.

“We found that patients with OA and AVN had better functional outcomes and those with AVN worse pain outcomes after primary THA, compared to patients with RA/inflammatory arthritis,” Singh and Lewallen. “Insights into mediators of these relationships are needed to better understand these associations.”

Reference

Singh JA, Lewallen DG. Patients with osteoarthritis and avascular necrosis have better functional outcomes and those with avascular necrosis worse pain outcomes compared to rheumatoid arthritis after primary hip arthroplasty: a cohort study. BMC Med. 2013 Sep 24;11(1):210. [Epub ahead of print]


 

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