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Experts refine nomenclature for eosinophilic GI diseases
The consensus paper defines subtypes for clinical and research purposes.
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Experts refine nomenclature for eosinophilic GI disorders
The consensus paper defines subtypes for clinical and research purposes.
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When cisplatin won’t do, try carboplatin in head and neck cancer
A retrospective analysis suggests carboplatin is better than cetuximab as a radiosensitizing agent.
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Mutation burden predicts ICI response in lung cancer
Novel biomarker combined with PD-L1 expression could indicate selection of immunotherapy and avoid chemotherapy toxicities in some patients.
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Fine-tuning HR-ARM for constipation diagnoses
Study authors suggest that reduced rectoanal gradient during high-resolution anorectal manometry could be enough reason to start biofeedback...
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In stage IIIA melanoma, nodal tumor size could guide decision-making
Sentinel node tumors 3 mm or larger should be considered for adjuvant therapy, while smaller sizes could be treated similarly to AJCC IB.
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Neoadjuvant immunotherapy shows promise for resectable CSCC
Response to treatment may lead to a reduction in potentially disfiguring surgeries.
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Weight gain linked to cancer survival in men and women
The finding underscores the need for nutritional support emphasized in 2020 ASCO guidelines.
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High BMI linked to better survival for cancer patients treated with ICI, but for men only
The reasons behind the findings and implications for treatment are unknown, as is whether it applies to patients with specific cancers.
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Early trial supports hypofractionated radiotherapy in uterine cancer
Early toxicity results are encouraging, but long-term efficacy and safety remain unknown.
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Time to cancer diagnoses in U.S. averages 5 months
Diagnosis time varied significantly across tumor types, as well as within the same tumor type.
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BRAF/MEK combo shows long-term efficacy in melanoma
Despite positive results, immunotherapy likely remains the best choice for first-line treatment of BRAFV600 mutated advanced melanoma.
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Annual screening benefits people at high-risk for pancreatic cancer
Opponents of screening suggested while screening may identify cancer earlier, it doesn’t necessarily improve outcomes.
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In NSCLC, not all EGFR mutations are the same
Patients with the Ex20 insertion may buck trend by responding well to ICIs.
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In early NSCLC, comorbidities linked to survival
Respiratory and cardiometabolic comorbidities were associated with significantly worse overall survival in lung cancer.