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One in four NSCLC patients respond poorly to COVID-19 vaccine
The reasons are unclear, but point to the need for NSCLC patients to have titers checked.
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Treatment combo shows ‘clinical benefit’ in liver cancer trial
Combined TKI and ICI inhibitor shows clinical benefit, but it isn’t yet a candidate for first-line therapy.
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Taste dysfunction in head and neck cancer due to radiation dose
Researchers identified doses to the oral cavity that predicted 15%, 25%, and 50% probability of taste dysfunction.
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Novel guidance informs plasma biomarker use for Alzheimer’s disease
The Alzheimer’s Association offers guidance for biomarker use in clinical trials and memory clinics.
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Higher ADR continues to show ‘strong, consistent’ link with lower interval CRC
The reduction in risk over a broad range of ADRs underscores the importance of an effective colonoscopy.
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Prior decompensation in alcohol-associated hepatitis not an ‘absolute contraindication’ for early liver transplant
About half of all liver mortality is attributable to alcohol-associated liver disease, and transplantation is the sole alternative when...
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Life-threatening adverse events in liver cancer less frequent with ICI therapy
While tyrosine kinase inhibitors were found to be associated with more serious adverse events, both treatments had similar toxic effects.
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Lung cancer treatment combo may be effective after ICI failure
Phase 2 trial offers hope of a chemotherapy-free option for patients with advanced NSCLC.
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The shifting sands of lung cancer screening
Studies find encouraging trends of stage shifting and minority screening, but more work remains.
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Pembrolizumab for melanoma bittersweet, doctor says
“Until we can further define who the highest-risk patients are, I think it’s hard to give it to everyone,” one doctor says.
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New KRAS inhibitor shows promise in NSCLC
One out of three lung cancer patients previously treated with chemotherapy and immune therapy responded to a new targeted therapy.
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New insights into worldwide biliary tract cancer incidence, mortality
Previous studies have examined worldwide BTC incidence; few looked at multiple global regions or at all subtypes.
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IBD study hints at cause of postacute COVID
Persistent viral antigens could be behind multiorgan symptoms: The majority of patients with gut antigen persistence had symptoms of postacute...
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Two genetic intestinal diseases linked
These rare conditions have separate genetic mutations but can share symptoms; new evidence suggests the two mutated proteins work together.
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ASCO outlines optimal treatments for patients with metastatic clear cell renal cell carcinoma
A dramatic increase in therapy options prompted the first guidance issued by ASCO earlier this year.