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LDL cholesterol triglycerides ‘robust’ ASCVD risk marker
A large dual-method Danish population study identified high LDL triglyceride levels as a risk marker for atherosclerotic cardiovascular disease....
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Exacerbation history found flawed as COPD risk predictor
Exacerbation history alone is not the most accurate risk-prediction tool.
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DELIVER subanalysis ‘seals deal’ for dapagliflozin in HF
An analysis of the large global DELIVER trial found that dapagliflozin improved outcomes and symptoms across a wide range of heart failure...
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Seizures in dementia hasten decline and death
Dementia patients who also had active seizures had shorter life expectancy and earlier decline than dementia patients who didn’t have active...
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Three antiseizure medications join list for newborn risks
A Scandinavian study of 4.5 million births adds carbamazepine, oxcarbazepine, and topiramate to list of antiseizure drugs linked to low birth...
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Randomized trial finds DMARD therapy for RA has a beneficial effect on vascular inflammation, CV risk
Receipt of a tumor necrosis factor inhibitor or triple therapy for rheumatoid arthritis yielded an equally beneficial effect for reducing vascular...
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Study implicates myelin plasticity in absence seizures
Researchers have found that changes in the insulating layer around nerves and axons in the brain may explain the progression of absence seizures...
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Newer brand-name drugs fuel spending on antiseizure medications
Rapid adoption of newer antiseizure medications has pushed increases in government spending that outpace the growth of prescriptions themselves....
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Novel PCI screening approach detects diffuse CAD
Pullback pressure gradient pre-PCI can differentiate diffuse and focal coronary artery disease.
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HDL cholesterol not linked to CHD risk in Blacks: REGARDS
A large biracial cohort study found that low levels of high-density lipoprotein cholesterol don’t raise heart disease risk in Black patients.
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ACR and EULAR roll out updated antiphospholipid syndrome criteria
A joint planning group proposes updates to 16-year-old criteria for classifying antiphospholipid syndrome.
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Denosumab may halt erosive hand OA progression
In a randomized clinical trial, denosumab seemed to halt progression of erosive hand osteoarthritis, but had a delayed impact on pain.
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StopRA trial: Hydroxychloroquine doesn’t prevent or delay onset of rheumatoid arthritis
A randomized clinical trial found that hydroxychloroquine was no more effective than placebo at preventing or delaying onset of rheumatoid...
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Combination therapy shows mixed results for scleroderma-related lung disease
A study of mycophenolate mofetil alone and in combination with pirfenidone for scleroderma-related interstitial lung disease showed mixed results...
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Combination therapy may boost remission in JIA
Study shows early methotrexate plus a biologic may aid remission and disease inactivity in pediatric polyarticular juvenile idiopathic arthritis...