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Rituximab ‘a reasonable alternative to cyclophosphamide’ to improve ILD-CTD
A clinical trial found that rituximab and cyclophosphamide had similar outcomes for interstitial lung disease associated with connective tissue...
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Ten-day methotrexate pause after COVID vaccine booster enhances immunity against Omicron variant
Researchers in Germany report a 10-day post-vaccination hold on methotrexate boosts immunity against Omicron without compromising safety or risk...
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Diabetes becoming less potent risk factor for CVD events
Diabetes is no longer equal to cardiovascular disease as a risk factor for cardiovascular events, according to a population-based study in Ontario...
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COVID pandemic associated with anorexia in Canadian youth
“There was so much disruption and [so many] restrictions to young peoples’ daily routines ... That led to heightened anxiety and depression and...
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NSAIDs linked to heart failure risk in diabetes
A Danish case-crossover study found that NSAID use increased heart failure risks 50% in patients with diabetes.
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Cholesterol levels lowering in U.S., but disparities emerge
While cholesterol levels in American adults have improved overall in the past decade, disparities in control have emerged, according to a new...
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Antibiotic before oral surgery spares endocarditis; study validates guidelines
“You have to have this [antibiotic prophylaxis] conversation when you see your patient with a prosthetic valve or who’s had endocarditis every...
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Gut metabolites may explain red meat–ASCVD link
A large cohort study implicates gut microbiome metabolites as the key link between red meat consumption and atherosclerotic cardiovascular disease...
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Is prostasin a clue to diabetes/cancer link?
Elevated plasma prostasin levels may be a potential biomarker of diabetes and cancer mortality, according to a Swedish prospective, population-...
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Is Lp(a) a marker for aortic calcium onset?
A link between elevated lipoprotein(a) and new-onset aortic valve calcification is found, but not necessarily calcium progression.
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Metabolic syndrome raises dementia risk in under-60s
A large follow-up study found a link between dementia risk and the number of components of metabolic syndrome a person has a midlife.
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Nurses’ cohort study: Endometriosis elevates stroke risk
Cohort study links endometriosis to an increased lifetime stroke risk.
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Study links sleep and objective, subjective cognition
Poor sleep efficiency may contribute to older adults overestimating their cognitive abilities, pointing to the need for objective cognitive...
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Long-term erratic sleep may foretell cognitive problems
An analysis of a large, decades-long sleep study has found a possible link between years-long inefficient sleep and cognitive impairment.