Clinical Review

Asphyxiation by Cake: An Unusual Case of Dyspnea

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Other case presentations
Similar cases have been described in the literature. In one case, following Hurricane Ivan, a 34-year-old man placed four 25-pound blocks of dry ice wrapped in paper in the front seat of his truck with the windows closed.5 After driving less than one-quarter of a mile, he developed dyspnea and telephoned for help before losing consciousness. Fortunately, he was found in time and recovered soon after the doors to his truck were opened.5

In another case, a 59-year-old man entered a walk-in freezer that contained dry ice wrapped loosely in plastic. He was found inside the freezer 20 minutes later in cardiac arrest; resuscitation efforts were unsuccessful. Investigation of the freezer found an initial O2 concentration of 13% (normal level, 20.93%) and an estimated CO2 level of 40%.5

Similarly, a 35-year-old woman was inadvertently locked in a bank vault while storing receipts. In a bid for help, she pulled the fire alarm, which triggered a CO2-based fire-extinguishing system. The fire department responded and found the woman dead in the vault 30 minutes later. The cause of death was labeled as CO2 intoxication.6

Natural phenomena
There have also been documented cases of CO2 toxicity associated with volcanic eruption and other natural phenomena; for example, the Lake Nyos, Cameroon, West Africa incident in 1986. In this event, a magma pocket underlying the lake saturated the water with CO2 stored as carbonic acid in the water. When a landslide hit the lake, it caused the carbonic acid stored in the depths of the lake to be upheaved to the surface, where it turned back into CO2 and was released into the atmosphere. Since CO2 is heavier than O2, it displaced the O2 near the ground, resulting in the suffocation and death of 1,700 people in the surrounding villages.2

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