Clinical Edge Journal Scan

Joint pain drives higher analgesic use in psoriasis


 

Key clinical point: Use of analgesics was higher in patients with psoriasis, particularly those with concomitant psoriatic arthritis (PsA), which could be because of increased joint pain.

Major finding: Moderate-to-severe joint pain was reported by 69% vs 45% of patients with vs without PsA ( P less than .0001). Patients with psoriasis vs reference individuals used more nonsteroidal anti‐inflammatory drugs (NSAIDS; 21.0% vs 17.3%) and opioids (14.2% vs 9.0%) within 1 year. Use of NSAIDS (30.8%) and opioids (22.7%) was even higher in patients with psoriasis and PsA. Of all symptoms, only joint pain seemed to be associated with the use of analgesics ( P less than .05).

Study details: Findings are from a cross-sectional study of 4,016 adults with psoriasis including 847 with concomitant PsA and 3,490 reference individuals.

Disclosures: No source of funding was declared. Dr. Loft, Dr. Kristensen, and Dr. Egeberg declared being speakers, receiving fees for speaking and consultancy, and/or research funding from various sources. Dr. Nguyen and Dr. Thyssen declared no potential conflict of interests.

Source: Loft N et al. J Am Acad Dermatol. 2021 Jul 24. doi: 10.1016/j.jaad.2021.07.028 .

Recommended Reading

The Top 100 Most-Cited Articles on Nail Psoriasis: A Bibliometric Analysis
MDedge Dermatology
Western diet promoted skin, joint inflammation in preclinical study
MDedge Dermatology
Anecdote Increases Patient Willingness to Take a Biologic Medication for Psoriasis
MDedge Dermatology
Update on Biologics for Psoriasis in Clinical Practice
MDedge Dermatology
Psoriatic Arthritis Diagnosis and Management in the Era of Telehealth
MDedge Dermatology
Translating the 2019 AAD-NPF Guidelines of Care for Psoriasis With Attention to Comorbidities
MDedge Dermatology
Psoriatic arthritis health care costs continue to rise over time
MDedge Dermatology
Bimekizumab approved in Europe for psoriasis treatment
MDedge Dermatology
Apremilast shows promise for mild-to-moderate psoriasis in phase 3
MDedge Dermatology
Risk for serious infection and biologics use in psoriasis: Is there a link?
MDedge Dermatology