Key clinical point: Atopic dermatitis (AD) was negatively associated with some serum lipids, indicating AD being intrinsically protective for dyslipidemia.
Major finding: AD was significantly associated with lower levels of total cholesterol (β −0.004; P < .001), triglycerides (β −0.006; P = .006), and low-density lipoprotein (β −0.004; P < .001) but not with high-density lipoprotein ( P = .794).
Study details: The data come from a large-scale, cross-sectional study including 13,822 patients with AD and 67,896 patients with asthma.
Disclosures: This study was supported by the National Key Research and Development Project of China Precision Medicine Initiative and the Program of Introducing Talents of Discipline to Universities. The authors declared no conflict of interests.
Source: Tang Z et al. Association between atopic dermatitis, asthma, and serum lipids: A UK Biobank based observational study and Mendelian randomization analysis. Front Med. 2022 (Feb 21). Doi: 10.3389/fmed.2022.810092