Key clinical point: Age, sex, body mass index (BMI), onset age of atopic dermatitis (AD), smoking habits, presence of palmar hyperlinearity, and other atopic diseases determine the disease severity in patients with AD.
Major finding: Compared with patients with mild AD, those with severe AD were usually older ( P = .020) and male ( P = .002) with an early onset age of AD (<2 years; P = .004), higher BMI ( P < .000), history of smoking ( P = .012), concomitant asthma ( P = .001), palmar hyperlinearity ( P = .013), hand dermatitis ( P = .020), history of contact allergy ( P = .042), and higher immunoglobulin E levels ( P < .0001).
Study details: Findings are from a single-center, cross-sectional observational study including 502 Finnish patients with AD, of which 146, 231, and 125 patients had mild, moderate, and severe AD, respectively.
Disclosures: This study did not receive any funding. The authors declared no conflicts of interest.
Source: Salava A et al. Factors associated with severity of atopic dermatitis - a Finnish cross-sectional study. J Eur Acad Dermatol Venereol. 2022 (Jun 29). Doi: 10.1111/jdv.18378