Ronda S. Farah, MD; Heather M. Holahan, BA; Brian L. Swick, MD
Giant cell tumor of the tendon sheath (GCTTS) is a benign neoplasm that typically presents on the hands. These lesions commonly are seen in the fourth decade of life and typically affect women. Physical examination typically reveals a painless asymptomatic nodule on the finger with a clinical history of slow growth over several months or years.