Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Inadequate Glycemic Control in Type 1 Diabetes Leads to Increased Fracture Risk

Publish date:: August 3, 2019

Key clinical point: A percentage increase in hemoglobin A_1c is significantly associated with an increase in fracture risk in patients with newly diagnosed type 1 diabetes.

Major finding: Each percentage increase in hemoglobin A_1c was associated with a 7% increase in fracture risk (95% confidence interval, 3%-12%).

Study details: A retrospective cohort study of 5,368 U.K. patients with newly diagnosed type 1 diabetes.

Disclosures: The study was not funded. The authors reported no conflicts of interest.

Citation:

Thayakaran R et al. Diab Med. 2019 Mar 8. doi: 10.1111/dme.13945.

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