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Protective action of impaired fasting glucose on osteoporosis risk
Key clinical point: Patients with impaired fasting glucose (IFG) and diabetes mellitus (DM) have a lower risk for incident osteoporosis.
Major finding: The risk of osteoporosis significantly decreased (P less than .001 for all) above the fourth quartile of fasting glucose levels in men and above the third quartile in women compared with the first quartile. The risk of osteoporosis was significantly lower (P less than .001 for all) with IFG (men: hazard ratio [HR], 0.84; women: HR, 0.93) and DM (men: HR, 0.77; women: HR, 0.75) compared with the normal glucose group.
Study details: The data come from a retrospective study of 96,626 patients.
Disclosures: No study sponsor was identified. The authors declared no conflicts of interest.
Park SK et al. Bone. 2020 Oct 21. doi: 10.1016/j.bone.2020.115690.