Key clinical point: The incidence of chronic myeloid leukemia (CML) has increased globally, but the declining death rate indicates improved treatment options. However, patient management, particularly among elderly patients, needs more attention.
Major finding: The incident cases of CML increased globally by 54.1% from 1990 to 2019. The overall age-standardized death rate declined by 2.55% per year, and disease-adjusted life years (DALY) decreased by 2.69% per year. However, patients aged 70-84 years accounted for higher CML incidence and death cases. Smoking was the biggest risk factor for CML-related DALY (12.2%).
Study details: This study used annual data on the CML burden in 204 countries and regions from 1990 to 2019.
Disclosures: This study was supported by the National Natural Science Foundation of China, Taishan Scholars Program, and Clinical Research Project of Shandong University. The authors declared no conflict of interests.
Source: Hu Y et al. JCO Glob Oncol. 2021 (Sep 30);7:1429-1441. doi: 10.1200/GO.21.00194.