Key clinical point: The association between metachronous colorectal cancer (CRC) diagnosis and biopsy of nontumor sites after biopsy of an initial CRC in the same colonoscopy is not significant.
Major finding: Nontumor site biopsy after initial CRC biopsy was not significantly associated with the risk for metachronous CRC in the colonic segment of the additional biopsy site (adjusted odds ratio 2.29; 95% CI 0.77-6.81).
Study details: This retrospective case-control study included 45 adult patients, diagnosed with CRC by colonoscopy with biopsy who underwent complete curative resection and were re-diagnosed with CRC within 6 months to 4 years of the initial diagnosis, and 212 matched control individuals.
Disclosures: The study was supported by the Population-based Research to Optimize the Screening Process Consortium, US National Cancer Institute. The authors declared no conflicts of interest.
Source: Lam AY et al. Biopsy of non-tumor sites after biopsy of a colorectal cancer is not associated with metachronous cancers: a case-control study. Clin Gastroenterol Hepatol. 2022 (May 26). Doi: 10.1016/j.cgh.2022.05.006