From the Journals

Prices, out-of-pocket costs for MS drugs rose despite competition


 

FROM JAMA NEUROLOGY

What are neurologists’ responsibilities?

Although the original annual price of interferon beta-1b ($10,920) was stunning, physicians now recall it with nostalgia, wrote Daniel M. Hartung, PharmD, associate professor of biostatistics and epidemiology, and Dennis Bourdette, MD, professor of neurology, both at Oregon Health and Science University, Portland, in an accompanying editorial. “The prices for DMTs for MS have risen dramatically over the last 15 years, far outpacing inflation, and now have a mean price of more than $86,000 per year.”

Dr. Dennis Bourdette

Dr. Dennis Bourdette

Neurologists should be concerned about these rising prices, Dr. Hartung and Dr. Bourdette wrote. They should feel responsibility toward the health care system that pays for these medications, and toward patients who pay out of their own pockets. “Neurologists should be seeking to minimize the financial adverse effects of these therapies as much as they try to minimize physical adverse effects.”

One way for neurologists to address increasing prices is to urge state and federal lawmakers to pass legislation to curb them, they wrote. Neurologists also should reexamine their relationships with pharmaceutical and biotechnology companies. “Remaining silent should not be an option. ... Neurologists should not allow the unfettered increases in price for these drugs to hurt the health care system or patients.”

The Myers Family Foundation and the National Heart, Lung, and Blood Institute funded the research. Several authors are employees of health insurance companies such as the UPMC Health Plan Insurance Services Division and Humana. One author received personal fees from Pfizer that were unrelated to this study.

SOURCEs: San-Juan-Rodriguez A et al. JAMA Neurol. 2019 Aug 26. doi: 10.1001/jamaneurol.2019.2711; Hartung DM and Bourdette D. JAMA Neurol. 2019 Aug 26. doi: 10.1001/jamaneurol.2019.2445.

Pages

Recommended Reading

General neurologists lag on prescribing high-efficacy MS drugs
Journal of Clinical Outcomes Management
Hazardous cannabis use in MS linked to anxiety, depression
Journal of Clinical Outcomes Management
MS patients pay big price for breaks from DMT
Journal of Clinical Outcomes Management
Developing new measurements for better MS outcomes
Journal of Clinical Outcomes Management
Balancing privacy, protection in at-risk MS patients
Journal of Clinical Outcomes Management
In MS, the challenges for women are unique
Journal of Clinical Outcomes Management
Patient registry sheds light on the economic impact of MS
Journal of Clinical Outcomes Management
Functional GI disorders are common in MS
Journal of Clinical Outcomes Management
Obesity tied to relapse in young patients with multiple sclerosis
Journal of Clinical Outcomes Management
Vaccination is not associated with increased risk of MS
Journal of Clinical Outcomes Management