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Memory tests in 50s predict mild cognitive impairment in middle age
Key clinical point: Memory performance of cognitively healthy adults in their 50s predicted progression to mild cognitive impairment 6 years later.
Major finding: A latent factor score combining seven memory measures was a significant predictor of amnestic mild cognitive impairment after 6 years in cognitively normal men (odds ratio 9.88).
Study details: The data come from a longitudinal study of 849 men who were cognitively normal at baseline and followed for approximately 6 years.
Disclosures: The study was supported by the National Institutes of Health. The researchers had no financial conflicts to disclose.
Gustavson DE et al. Alzheimers Dement (Amst). 2020 Apr 11. doi: 10.1002/dad2.12004.