Key clinical point: The leptin/body mass index (BMI) ratio was higher in women with psoriatic arthritis (PsA) than in men with the disease and was also associated with pain intensity in women.
Major finding: The leptin/BMI ratio was significantly higher in women than in men (median 0.8 vs 0.2; P < .001). Pain intensity was associated with the leptin/BMI ratio in women ( β 0.29; P < .004), while there was no significant association in men ( P = .46).
Study details: This observational cross-sectional study included 203 patients with PsA aged 18 years or older, of whom 46.8% were women.
Disclosures: This study did not receive any external funding. The authors declared no conflicts of interest.
Source: Toledano E, Gómez-Lechón L, Chacón CC, et al. Clinical features and disease activity in psoriatic arthritis: A sex-related perspective on leptin and comorbidity. J Clin Med. 2024;13(10):2959 (May 17). doi: 10.3390/jcm13102959 Source