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Is diagnostic hysteroscopy safe in patients with type 2 endometrial cancer?
Key clinical point: Among women with type 2 endometrial cancer, diagnostic hysteroscopy may not be associated with increased odds of positive peritoneal cytology at the time of surgical staging or with decreased survival.
Major finding: Positive peritoneal cytology was more common among patients who underwent curettage than among patients who underwent hysteroscopy (10.7% vs. 4.6%), although the difference was not statistically significant. Lymphovascular invasion and advanced surgical staging were more common in the curettage group. In a multivariate analysis, older age and advanced cancer staging were the only factors associated with decreased disease-free survival. Age, advanced cancer staging, and vascular invasion were associated with decreased disease-specific survival.
Study details: A retrospective study of 127 patients with type 2 endometrial cancer.
Disclosures: The researchers had no relevant financial disclosures.
Oliveira Brito LG et al. J Minim Invasive Gynecol. 2020 Nov. doi: 10.1016/j.jmig.2020.08.356.