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Younger men and women show similar rates of osteopenia
A new study finds that about a quarter of both men and women in early middle age have osteopenia in at least one site.
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Warfarin found to increase adverse outcomes among patients with IPF
DALLAS – Among patients with IPF who need anticoagulation, warfarin increased the risk of both lung transplant and death, while direct oral...
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Coding variants in apolipoprotein B may be associated with early-onset Alzheimer’s disease
The finding may help fill out the genetic risk picture for early-onset Alzheimer’s disease.
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mTORC1 inhibitor protects elderly asthmatics from viral respiratory tract infections
DALLAS – By boosting innate immunity, RBT101 protects against rhinovirus respiratory infections and decreases the asthma exacerbations that can be...
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Nintedanib cut lung function decline in interstitial lung disease with systemic sclerosis
DALLAS – A decline in FVC is a good surrogate marker of mortality in interstitial lung disease associated with...
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Ultrasound offers advantages for long-term lymph node surveillance in high-grade SCC patients
BALTIMORE – Compared with other imaging modalities, ultrasound gives more anatomic details and costs much less.
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Plasma levels of neurofilament light track neurodegeneration in MCI and Alzheimer’s disease
The protein also may be useful to monitor effects in trials of disease-modifying drugs.
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Extended half-life clotting factors cut infusions, hike prices
The use of extended half-life clotting factors was able to significantly reduce the number of infusions but the cost went up significantly.
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Hip T scores can guide duration of osteoporosis therapy
A treat-to-target approach using total hip T scores could help guide decisions about how long women with osteoporosis should stay on bone-building...
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Poor response to statins hikes risk of cardiovascular events
Patients with better outcomes were more likely to have initiated therapy with a more potent drug.
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FDA orders companies to cease all sales of transvaginal mesh for POP repair
The manufacturers didn’t provide the required safety and efficacy data in their premarket applications.
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BACE-1 inhibition worsens cognition in patients with prodromal Alzheimer’s disease
Inhibiting the APP-cleaving enzyme decreased the toxic amyloid species, but it also worsened cognition and caused a variety of concerning adverse...
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Ligelizumab maintains urticaria control for up to 1 year
WASHINGTON – The open-label extension trial found a good maintenance of effect in patients with chronic spontaneous urticaria that is...
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Pembrolizumab benefits some patients with advanced cervical cancer
The checkpoint inhibitor was especially effective in patients with PD-L1-positive tumors.