Key clinical point: A significant positive association exists between elevated levels of serum uric acid (SUA) and the risk for incident colorectal cancer (CRC).
Major finding: SUA levels and the risk for CRC showed a positive dose-response and linear association (P = .004), with the risk for incident CRC being 1.55-fold higher among participants in the highest vs lowest tertile of SUA levels (adjusted hazard ratio 1.55; P = .019).
Study details: Findings are from an ongoing prospective cohort study including 93,356 cancer-free participants.
Disclosures: This study did not report any source of funding. The authors declared no conflicts of interest.
Source: Li W et al. The relationship between serum uric acid and colorectal cancer: A prospective cohort study. Sci Rep. 2022;12:16677 (Oct 6). Doi: 10.1038/s41598-022-20357-7