CNS/Brain Cancer
Conference Coverage
Childhood cancer survivors face several long-term risks
Despite improvements, survivors of childhood cancers still face long-term risks in terms of secondary neoplasms, nonsurgical premature menopause (...
Conference Coverage
Temozolomide + RT boosts survival in elderly with glioblastoma
Key clinical point: Combining temozolomide with radiotherapy prolongs survival for elderly with glioblastoma. Major finding: Combining...
Conference Coverage
Tandem beats single ASCT for childhood neuroblastoma
Key clinical point: Neuroblastoma event-free survival was better with tandem than with single ASCT. Major finding: Event-free survival was 61%...
Conference Coverage
IL-2 adds only toxicity to neuroblastoma antibody tx
Key clinical point: IL-2 adds no benefit, only toxicity, to neuroblastoma antibody therapy. Major finding: Only 61% of treatment cycles were...
News
Adjuvant temozolomide increases survival in rare anaplastic glioma
Key clinical point: Adjuvant temozolomide post-radiation improves survival in non-1p/19q-deleted anaplastic glioma. Major finding: Adjuvant...
News
Early results positive for treating high-grade gliomas with virus-based therapy
Key clinical point: A phase I trial indicates that Toca 511 is safe and shows activity in treating patients with high-grade or recurrent...
News
Investigational CDK4/6 inhibitor shows activity, less toxicity
Key clinical point: A phase I trial indicates that abemaciclib is safe and shows activity in treating patients with advanced breast and other...
News
Targeting gene rearrangements shows promise in early study
Key clinical point: Entrectinib showed antitumor activity including intracranial responses.
News
Adding chemo to radiation boosts survival from low-grade gliomas
Key clinical point: Adding chemotherapy to radiotherapy improved progression-free survival and overall survival in patients with low-grade glioma...
News
Temsirolimus results in good but short-duration responses in primary CNS lymphoma
Key clinical point: Relapsed/refractory primary CNS lymphoma has a poor prognosis and no standard treatment option. Major finding: The overall...