Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

Chronic migraine is associated with changes in the amygdala

Publish date:: May 27, 2020

Key clinical point: Structural and functional changes in the amygdala may contribute to transformation from episodic to chronic migraine.

Major finding: Connectivity between the amygdala and default mode network is positively associated with headache frequency in migraineurs.

Study details: An observational study of 44 patients with episodic migraine and 44 patients with chronic migraine.

Disclosures: Dr. DeSouza reported no disclosures. One of the investigators acts as an advisor to Alder, Allergan, Amgen, Biohaven, Curex, Teva, and Xoc about matters unrelated to this study.

Citation:

DeSouza DD et al. AAN 2020, Abstract 46914.

This Week's Must Reads

COVID-19 vaccine found effective but doctors watching for reactions, adverse events,

Study links sleep meds and dementia risk in older adults,

Childhood Hodgkin survivors have neurocognitive impairment,

Obesity, hypoxia predict severity in children with COVID-19,

Long-term safety and efficacy of teriflunomide for relapsing MS,

Must Reads in Headache & Migraine

HIT-6 may help track meaningful change in chronic migraine,

Choroid plexuses may play a role in migraine,

Multiple traits more common in difficult-to-treat patients with migraine,

Marijuana for migraine? Some tentative evidence,

Low vitamin D levels in patients with migraine,