Key clinical point: Levonorgestrel was noninferior to copper IUD for emergency contraception, with similar pregnancy rates and adverse events reported for both methods.
Major finding: Pregnancy rates were 1 in 317 (0.3%) in the levonorgestrel group and 0 in 321 (0%) in the copper IUD group in the modified intent-to-treat analysis.
Study details: The data come from a randomized trial of 317 women who received levonorgestrel IUD and 321 who received copper IUDs and provided 1-month outcome data.
Disclosures: The study was supported by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD); the University of Utah, with funding in part from the National Institutes of Health (NIH) National Center for Research Resources and National Center for Advancing Translational Sciences; and grants to the lead author and several coauthors from the NIH Office of Research on Women’s Health and the Eunice Kennedy Shriver NICHD.
Source: Turok DK et al. N Engl J Med. 2021 Jan 28. doi: 10.1056/NEJMoa2022141.