News
FDA Approves Pfizer’s Hympavzi for Hemophilia A, B
- Author:
- M. Alexander Otto, PA, MMS
New weekly injection treatment option to prevent or reduce bleeding in hemophilia A and B for patients aged 12 and older gets FDA approval.
News
Popular Weight Loss Drugs Now for Patients With Cancer?
- Author:
- M. Alexander Otto, PA, MMS
Research suggests that obesity can reduce the effectiveness of cancer therapies.
News
FDA Panel Votes for Limits on Gastric, Esophageal Cancer Immunotherapy
- Author:
- M. Alexander Otto, PA, MMS
The FDA’s Oncologic Drugs Advisory Committee (ODAC) voted in favor of restricting the use of these immunotherapy agents to patients with PD-L1...
News
FDA OKs Adjuvant Ribociclib in Earlier Stage Breast Cancer
- Author:
- M. Alexander Otto, PA, MMS
The FDA also approved ribociclib and the aromatase inhibitor letrozole packaged together for the same indication.
News
Isatuximab Approved First-Line for Transplant-Ineligible MM
- Author:
- M. Alexander Otto, PA, MMS
FDA greenlighted expansion of a biologic to treat patients newly diagnosed with myeloma for whom transplants are not an option.
News
KRAS Inhibitors in Pancreatic Cancer: Hope on the Horizon?
- Author:
- M. Alexander Otto, PA, MMS
A pipeline of KRAS inhibitors targeting pancreatic cancer has emerged.
News
FDA Issues Complete Response Letter for Myeloma Drug
- Author:
- Victoria Stern
- M. Alexander Otto, PA, MMS
FDA declines to approve linvoseltamab for treatment of relapsed/refractory multiple myeloma, citing issues at a third-party manufacturer.
News
Clinical Controversy: Watch-and-Wait or Surgery in Rectal Cancer Near Complete Responders?
- Author:
- M. Alexander Otto, PA, MMS
Watch-and-wait for near-complete clinical responders is “very controversial.”
News
FDA Approves Neoadjuvant/Adjuvant Durvalumab for NSCLC
- Author:
- M. Alexander Otto, PA, MMS
The drug was approved alongside platinum-containing chemotherapy in the neoadjuvant setting and as monotherapy in the adjuvant setting.
News
Immunotherapy May Be Overused in Dying Patients With Cancer
- Author:
- M. Alexander Otto, PA, MMS
“There are patients who are getting immunotherapy who shouldn’t,” according to a surgical oncologist from Yale.
News
FDA Approves First Engineered Cell Therapy for a Solid Tumor
- Author:
- M. Alexander Otto, PA, MMS
- Victoria Stern, MA
This T-cell receptor therapy modifies existing receptors to recognize an array of antigens on the surface of cancer cells.
News
FDA Calls AstraZeneca’s NSCLC Trial Design Into Question
- Author:
- M. Alexander Otto, PA, MMS
ODAC: A trial’s design makes it impossible to tell whether patients with resectable NSCLC tumors benefited from durvalumab before surgery, after...
News
Clinical Controversy: Standard Dose or Baby TAM for Breast Cancer Prevention?
- Author:
- M. Alexander Otto, PA, MMS
Docs debate which dose of tamoxifen is best for reducing breast cancer risk at the ESMO Breast Cancer Congress.
News
FDA Approves Epcoritamab for R/R Follicular Lymphoma
- Author:
- M. Alexander Otto, PA, MMS
The approval was based on the single-arm EPCORE NHL-1 trial in 127 patients who had received at least two lines of systemic therapy.
News
Thermal Ablation Tops Surgery for Small CRC Liver Mets
- Author:
- M. Alexander Otto, PA, MMS
The benefit of thermal ablation was so substantial that the trial was stopped early.