Research and Reviews for the Practicing Oncologist

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Survivorship care planning in a comprehensive cancer center using an implementation framework

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Survivorship care planning in a comprehensive cancer center using an implementation framework

Cancer survivorship care plans have been recommended to improve clinical care and patient outcomes. We describe here how we established routine SCP delivery at the Robert H Lurie Comprehensive Cancer Center in Chicago, Illinois, using the Quality Implementation Framework. We evaluated local practices, gathered clinician and patient stakeholder input, developed customized SCP templates within the electronic health record, and implemented 2 complementary delivery models.

 

Click on the PDF icon at the top of this introduction to read the full article.

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The Journal of Community and Supportive Oncology - 14(5)
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192-199
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survivorship, survivorship care plan, SCP, electronic health record, follow-up care, patient-centered care
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Cancer survivorship care plans have been recommended to improve clinical care and patient outcomes. We describe here how we established routine SCP delivery at the Robert H Lurie Comprehensive Cancer Center in Chicago, Illinois, using the Quality Implementation Framework. We evaluated local practices, gathered clinician and patient stakeholder input, developed customized SCP templates within the electronic health record, and implemented 2 complementary delivery models.

 

Click on the PDF icon at the top of this introduction to read the full article.

Cancer survivorship care plans have been recommended to improve clinical care and patient outcomes. We describe here how we established routine SCP delivery at the Robert H Lurie Comprehensive Cancer Center in Chicago, Illinois, using the Quality Implementation Framework. We evaluated local practices, gathered clinician and patient stakeholder input, developed customized SCP templates within the electronic health record, and implemented 2 complementary delivery models.

 

Click on the PDF icon at the top of this introduction to read the full article.

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The Journal of Community and Supportive Oncology - 14(5)
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The Journal of Community and Supportive Oncology - 14(5)
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192-199
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192-199
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Survivorship care planning in a comprehensive cancer center using an implementation framework
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Survivorship care planning in a comprehensive cancer center using an implementation framework
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survivorship, survivorship care plan, SCP, electronic health record, follow-up care, patient-centered care
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survivorship, survivorship care plan, SCP, electronic health record, follow-up care, patient-centered care
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Trabectedin expands treatment options for some forms of advanced soft tissue sarcoma

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Trabectedin expands treatment options for some forms of advanced soft tissue sarcoma
In the fall of 2015, the United States joined the growing list of countries in which trabectedin, a novel form of chemotherapy, is approved for the treatment of certain types of advanced soft tissue sarcoma. The drug, a synthetic derivative of a compound originally isolated from a sea squirt, has a complex mechanism of action that distinguishes it from other cytotoxic drugs, allowing it to target both the tumor and its microenvironment. Based on the results of a randomized, open-label, multicenter phase 3 clinical trial, trabectedin received regulatory approval for the treatment of unresectable or metastatic liposarcoma or leiomyosarcoma.

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

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The Journal of Community and Supportive Oncology - 14(5)
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189-191
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trabectedin, soft tissue sarcoma, ET743-SAR-3007, liposarcoma, leiomyosarcoma, dacarbazine
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In the fall of 2015, the United States joined the growing list of countries in which trabectedin, a novel form of chemotherapy, is approved for the treatment of certain types of advanced soft tissue sarcoma. The drug, a synthetic derivative of a compound originally isolated from a sea squirt, has a complex mechanism of action that distinguishes it from other cytotoxic drugs, allowing it to target both the tumor and its microenvironment. Based on the results of a randomized, open-label, multicenter phase 3 clinical trial, trabectedin received regulatory approval for the treatment of unresectable or metastatic liposarcoma or leiomyosarcoma.

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

In the fall of 2015, the United States joined the growing list of countries in which trabectedin, a novel form of chemotherapy, is approved for the treatment of certain types of advanced soft tissue sarcoma. The drug, a synthetic derivative of a compound originally isolated from a sea squirt, has a complex mechanism of action that distinguishes it from other cytotoxic drugs, allowing it to target both the tumor and its microenvironment. Based on the results of a randomized, open-label, multicenter phase 3 clinical trial, trabectedin received regulatory approval for the treatment of unresectable or metastatic liposarcoma or leiomyosarcoma.

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

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The Journal of Community and Supportive Oncology - 14(5)
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The Journal of Community and Supportive Oncology - 14(5)
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189-191
Page Number
189-191
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Trabectedin expands treatment options for some forms of advanced soft tissue sarcoma
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Trabectedin expands treatment options for some forms of advanced soft tissue sarcoma
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trabectedin, soft tissue sarcoma, ET743-SAR-3007, liposarcoma, leiomyosarcoma, dacarbazine
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Mining for information, participation in clinical trials

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Mining for information, participation in clinical trials
As you read this month’s May issue of the Journal of Community and Supportive Oncology, the world will be making plans to attend the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. Two things will happen there: investigators will present the latest, most important clinical and supportive care research findings in oncology, and leaders in the field will deliver educational session updates from the general to the most highly specialized areas of oncology. So how do we stay up to date in clinical practice these days?

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

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Issue
The Journal of Community and Supportive Oncology - 14(5)
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Page Number
187-188
Legacy Keywords
clinical trials, barriers, trabectedin, survivorship care plan, exercise interventions, breast cancer, nausea, vomiting, dexamethasone
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Article PDF
As you read this month’s May issue of the Journal of Community and Supportive Oncology, the world will be making plans to attend the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. Two things will happen there: investigators will present the latest, most important clinical and supportive care research findings in oncology, and leaders in the field will deliver educational session updates from the general to the most highly specialized areas of oncology. So how do we stay up to date in clinical practice these days?

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

As you read this month’s May issue of the Journal of Community and Supportive Oncology, the world will be making plans to attend the annual meeting of the American Society of Clinical Oncology (ASCO) in Chicago. Two things will happen there: investigators will present the latest, most important clinical and supportive care research findings in oncology, and leaders in the field will deliver educational session updates from the general to the most highly specialized areas of oncology. So how do we stay up to date in clinical practice these days?

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

Issue
The Journal of Community and Supportive Oncology - 14(5)
Issue
The Journal of Community and Supportive Oncology - 14(5)
Page Number
187-188
Page Number
187-188
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Mining for information, participation in clinical trials
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Mining for information, participation in clinical trials
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clinical trials, barriers, trabectedin, survivorship care plan, exercise interventions, breast cancer, nausea, vomiting, dexamethasone
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clinical trials, barriers, trabectedin, survivorship care plan, exercise interventions, breast cancer, nausea, vomiting, dexamethasone
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Multiple myeloma: newly approved drugs forge paradigm shift toward chronic disease

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Multiple myeloma: newly approved drugs forge paradigm shift toward chronic disease

The pace of drug development for multiple myeloma was dizzying in 2015, with 5 regulatory approvals for the treatment of relapsed/refractory disease, 3 in a single month. As we stand on the brink of another paradigm shift in the management of this disease, we discuss the new classes of drugs and how they are shaping standard of care with the potential to make multiple myeloma a chronic disease.

 

Click on the PDF icon at the top of this introduction to read the full article.

 

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Issue
The Journal of Community and Supportive Oncology - 14(4)
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Topics
Page Number
180-186
Legacy Keywords
multiple myeloma, immunomodulatory drugs, IMiDs, thalidomide, lenalidomide, proteasome inhibitors, bortezomib, carflzomib, dexamethasone, ixazomib, histone deacetylase, HDAC, panobinostat, monoclonal antibodies, mAb, elotuzumab, SLAMF7, daratumumab, CD38, immunotherapy, programmed cell death-1, PD-1, nivolumab, atezolizumab, ipilimumab
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The pace of drug development for multiple myeloma was dizzying in 2015, with 5 regulatory approvals for the treatment of relapsed/refractory disease, 3 in a single month. As we stand on the brink of another paradigm shift in the management of this disease, we discuss the new classes of drugs and how they are shaping standard of care with the potential to make multiple myeloma a chronic disease.

 

Click on the PDF icon at the top of this introduction to read the full article.

 

The pace of drug development for multiple myeloma was dizzying in 2015, with 5 regulatory approvals for the treatment of relapsed/refractory disease, 3 in a single month. As we stand on the brink of another paradigm shift in the management of this disease, we discuss the new classes of drugs and how they are shaping standard of care with the potential to make multiple myeloma a chronic disease.

 

Click on the PDF icon at the top of this introduction to read the full article.

 

Issue
The Journal of Community and Supportive Oncology - 14(4)
Issue
The Journal of Community and Supportive Oncology - 14(4)
Page Number
180-186
Page Number
180-186
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Multiple myeloma: newly approved drugs forge paradigm shift toward chronic disease
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Multiple myeloma: newly approved drugs forge paradigm shift toward chronic disease
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multiple myeloma, immunomodulatory drugs, IMiDs, thalidomide, lenalidomide, proteasome inhibitors, bortezomib, carflzomib, dexamethasone, ixazomib, histone deacetylase, HDAC, panobinostat, monoclonal antibodies, mAb, elotuzumab, SLAMF7, daratumumab, CD38, immunotherapy, programmed cell death-1, PD-1, nivolumab, atezolizumab, ipilimumab
Legacy Keywords
multiple myeloma, immunomodulatory drugs, IMiDs, thalidomide, lenalidomide, proteasome inhibitors, bortezomib, carflzomib, dexamethasone, ixazomib, histone deacetylase, HDAC, panobinostat, monoclonal antibodies, mAb, elotuzumab, SLAMF7, daratumumab, CD38, immunotherapy, programmed cell death-1, PD-1, nivolumab, atezolizumab, ipilimumab
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Acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine in a patient with pancreatic cancer

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Acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine in a patient with pancreatic cancer
Improvements in antiemetic therapy constitute a major advance in oncology. A recent poll of the oncology community by the American Society of Clinical Oncology ranked it as one of the top 5 advances in cancer in the last 50 years.1 Emetogenicity of chemotherapy is defined by risk of emesis in the patient given no antiemetics; high-risk regimens cause nausea and vomiting in >90% of patients, moderate risk in 30%-90%, and low risk in <30%.

 

Click on the PDF icon at the top of this introduction to read the full article. 
 
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The Journal of Community and Supportive Oncology - 14(4)
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Page Number
178-179
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pancreatic cancer, benzodiazepine, toxicity, olanzapine, antiemetic, nausea, vomiting, fumazenil
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Improvements in antiemetic therapy constitute a major advance in oncology. A recent poll of the oncology community by the American Society of Clinical Oncology ranked it as one of the top 5 advances in cancer in the last 50 years.1 Emetogenicity of chemotherapy is defined by risk of emesis in the patient given no antiemetics; high-risk regimens cause nausea and vomiting in >90% of patients, moderate risk in 30%-90%, and low risk in <30%.

 

Click on the PDF icon at the top of this introduction to read the full article. 
 
Improvements in antiemetic therapy constitute a major advance in oncology. A recent poll of the oncology community by the American Society of Clinical Oncology ranked it as one of the top 5 advances in cancer in the last 50 years.1 Emetogenicity of chemotherapy is defined by risk of emesis in the patient given no antiemetics; high-risk regimens cause nausea and vomiting in >90% of patients, moderate risk in 30%-90%, and low risk in <30%.

 

Click on the PDF icon at the top of this introduction to read the full article. 
 
Issue
The Journal of Community and Supportive Oncology - 14(4)
Issue
The Journal of Community and Supportive Oncology - 14(4)
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178-179
Page Number
178-179
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Acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine in a patient with pancreatic cancer
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Acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine in a patient with pancreatic cancer
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pancreatic cancer, benzodiazepine, toxicity, olanzapine, antiemetic, nausea, vomiting, fumazenil
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pancreatic cancer, benzodiazepine, toxicity, olanzapine, antiemetic, nausea, vomiting, fumazenil
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Severe eosinophilia associated with cholangiocarcinoma

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Severe eosinophilia associated with cholangiocarcinoma

It is widely recognized that eosinophils are found in tumor infiltrates and that their mechanism of action is associated with particular symptoms and prognosis. However, the causes of and reasons for this process remain unclear, as does the exact mechanism by which it occurs. We report on the case of a 71-year-old woman with cholangiocellar carcinoma (CCC) with a marked eosinophilia. When the patient presented at the hospital, she said she was suffering from fatigue, depression, and pain.

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

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The Journal of Community and Supportive Oncology - 14(4)
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Page Number
173-177
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eosinophilia, cholangiocarcinoma, cholangiocellar carcinoma, CCC, tumor-associated blood eosinophilia, TABE, tumor-associated tissue eosinophilia, tissue eosinophilia, TATE
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It is widely recognized that eosinophils are found in tumor infiltrates and that their mechanism of action is associated with particular symptoms and prognosis. However, the causes of and reasons for this process remain unclear, as does the exact mechanism by which it occurs. We report on the case of a 71-year-old woman with cholangiocellar carcinoma (CCC) with a marked eosinophilia. When the patient presented at the hospital, she said she was suffering from fatigue, depression, and pain.

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

It is widely recognized that eosinophils are found in tumor infiltrates and that their mechanism of action is associated with particular symptoms and prognosis. However, the causes of and reasons for this process remain unclear, as does the exact mechanism by which it occurs. We report on the case of a 71-year-old woman with cholangiocellar carcinoma (CCC) with a marked eosinophilia. When the patient presented at the hospital, she said she was suffering from fatigue, depression, and pain.

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

Issue
The Journal of Community and Supportive Oncology - 14(4)
Issue
The Journal of Community and Supportive Oncology - 14(4)
Page Number
173-177
Page Number
173-177
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Severe eosinophilia associated with cholangiocarcinoma
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Severe eosinophilia associated with cholangiocarcinoma
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eosinophilia, cholangiocarcinoma, cholangiocellar carcinoma, CCC, tumor-associated blood eosinophilia, TABE, tumor-associated tissue eosinophilia, tissue eosinophilia, TATE
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eosinophilia, cholangiocarcinoma, cholangiocellar carcinoma, CCC, tumor-associated blood eosinophilia, TABE, tumor-associated tissue eosinophilia, tissue eosinophilia, TATE
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David Henry's JCSO podcast, April 2016

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David Henry's JCSO podcast, April 2016

In his April podcast for The Journal of Community and Supportive Oncology, Editor-in-Chief Dr David Henry discusses Original Reports on olanzapine compared with fosaprepitant for the prevention of concurrent chemotherapy radiotherapy-induced nausea and vomiting and an analysis of patient-reported outcomes in prostate cancer after treatment with abiraterone acetate. Also among the line-up of Original Reports are studies looking at the diagnostic work-up for the detection of malnutrition in hospitalized cancer patients and at the use of video-conferencing to deliver cancer genetic counseling to high-risk underserved individuals. The Case Reports include an unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade, another of severe eosinophilia associated with cholangiocarcinoma, and a third on acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine. The Community Translations column features approvals of nivolumab approval for metastatic renal-cell carcinoma. Dr Henry also discusses a feature article on new therapies for multiple myeloma that are redefining the condition as a chronic disease.

 

Listen to the podcast below.

 

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Legacy Keywords
Immunotherapy, nivolumab, renal-cell carcinoma, RCC, olanzapine, fosaprepitant, chemotherapy-induced nausea and vomiting, CINV, patient-reported outcomes, PROs, prostate cancer, abiraterone acetate, malnutrition, underserved patients, genetic counseling, non-small-cell lung cancer, NSCLC, spontaneous cardiac tamponade, eosinophilia, cholangiocarcinoma, acute benzodiazepine, multiple myeloma
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In his April podcast for The Journal of Community and Supportive Oncology, Editor-in-Chief Dr David Henry discusses Original Reports on olanzapine compared with fosaprepitant for the prevention of concurrent chemotherapy radiotherapy-induced nausea and vomiting and an analysis of patient-reported outcomes in prostate cancer after treatment with abiraterone acetate. Also among the line-up of Original Reports are studies looking at the diagnostic work-up for the detection of malnutrition in hospitalized cancer patients and at the use of video-conferencing to deliver cancer genetic counseling to high-risk underserved individuals. The Case Reports include an unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade, another of severe eosinophilia associated with cholangiocarcinoma, and a third on acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine. The Community Translations column features approvals of nivolumab approval for metastatic renal-cell carcinoma. Dr Henry also discusses a feature article on new therapies for multiple myeloma that are redefining the condition as a chronic disease.

 

Listen to the podcast below.

 

In his April podcast for The Journal of Community and Supportive Oncology, Editor-in-Chief Dr David Henry discusses Original Reports on olanzapine compared with fosaprepitant for the prevention of concurrent chemotherapy radiotherapy-induced nausea and vomiting and an analysis of patient-reported outcomes in prostate cancer after treatment with abiraterone acetate. Also among the line-up of Original Reports are studies looking at the diagnostic work-up for the detection of malnutrition in hospitalized cancer patients and at the use of video-conferencing to deliver cancer genetic counseling to high-risk underserved individuals. The Case Reports include an unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade, another of severe eosinophilia associated with cholangiocarcinoma, and a third on acute benzodiazepine toxicity exacerbated by concomitant oral olanzapine. The Community Translations column features approvals of nivolumab approval for metastatic renal-cell carcinoma. Dr Henry also discusses a feature article on new therapies for multiple myeloma that are redefining the condition as a chronic disease.

 

Listen to the podcast below.

 

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David Henry's JCSO podcast, April 2016
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David Henry's JCSO podcast, April 2016
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Immunotherapy, nivolumab, renal-cell carcinoma, RCC, olanzapine, fosaprepitant, chemotherapy-induced nausea and vomiting, CINV, patient-reported outcomes, PROs, prostate cancer, abiraterone acetate, malnutrition, underserved patients, genetic counseling, non-small-cell lung cancer, NSCLC, spontaneous cardiac tamponade, eosinophilia, cholangiocarcinoma, acute benzodiazepine, multiple myeloma
Legacy Keywords
Immunotherapy, nivolumab, renal-cell carcinoma, RCC, olanzapine, fosaprepitant, chemotherapy-induced nausea and vomiting, CINV, patient-reported outcomes, PROs, prostate cancer, abiraterone acetate, malnutrition, underserved patients, genetic counseling, non-small-cell lung cancer, NSCLC, spontaneous cardiac tamponade, eosinophilia, cholangiocarcinoma, acute benzodiazepine, multiple myeloma
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An unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade

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An unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade

Hemorrhagic pericardial effusion with associated cardiac tamponade as a de novo sign of malignancy is seen in about 2% of patients.1 Consequently, cardiac tamponade is an oncologic emergency and considered a unique presentation of a malignancy.2 Cancer emergency is defined as an acute condition that is caused directly by the cancer itself or its treatment and requires intervention to avoid death or significant morbidity.3 The mechanism by which cardiac tamponade is classified as a life-threatening emergency stems from its impairment of right ventricular filling, resulting in ventricular diastolic collapse and decreased cardiac output, which can ultimately lead to death.4

 

Click on the PDF icon at the top of this introduction to read the full article.

 
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The Journal of Community and Supportive Oncology - 14(4)
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Page Number
169-172
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non-small-cell lung cancer, NSCLC, spontaneous cardiac tamponade, pericardial effusion, pulmonary emboli
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Hemorrhagic pericardial effusion with associated cardiac tamponade as a de novo sign of malignancy is seen in about 2% of patients.1 Consequently, cardiac tamponade is an oncologic emergency and considered a unique presentation of a malignancy.2 Cancer emergency is defined as an acute condition that is caused directly by the cancer itself or its treatment and requires intervention to avoid death or significant morbidity.3 The mechanism by which cardiac tamponade is classified as a life-threatening emergency stems from its impairment of right ventricular filling, resulting in ventricular diastolic collapse and decreased cardiac output, which can ultimately lead to death.4

 

Click on the PDF icon at the top of this introduction to read the full article.

 

Hemorrhagic pericardial effusion with associated cardiac tamponade as a de novo sign of malignancy is seen in about 2% of patients.1 Consequently, cardiac tamponade is an oncologic emergency and considered a unique presentation of a malignancy.2 Cancer emergency is defined as an acute condition that is caused directly by the cancer itself or its treatment and requires intervention to avoid death or significant morbidity.3 The mechanism by which cardiac tamponade is classified as a life-threatening emergency stems from its impairment of right ventricular filling, resulting in ventricular diastolic collapse and decreased cardiac output, which can ultimately lead to death.4

 

Click on the PDF icon at the top of this introduction to read the full article.

 
Issue
The Journal of Community and Supportive Oncology - 14(4)
Issue
The Journal of Community and Supportive Oncology - 14(4)
Page Number
169-172
Page Number
169-172
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An unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade
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An unusual case of non-small-cell lung cancer presenting as spontaneous cardiac tamponade
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non-small-cell lung cancer, NSCLC, spontaneous cardiac tamponade, pericardial effusion, pulmonary emboli
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non-small-cell lung cancer, NSCLC, spontaneous cardiac tamponade, pericardial effusion, pulmonary emboli
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Reaching high-risk underserved individuals for cancer genetic counseling by video-teleconferencing

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Reaching high-risk underserved individuals for cancer genetic counseling by video-teleconferencing

Background Breast and colorectal cancers are common cancers for which genetic risk assessment and counseling are available. However, these services are often limited to metropolitan areas and are not readily accessible to underserved populations. Moreover, ethnic and racial disparities present additional obstacles to identifying and screening high-risk individuals and have a bearing on treatment outcomes.

Objective To provide cancer genetic risk assessment and counseling through telemedicine to the remote, underserved primarily Hispanic population of the Texas-Mexico border region.

Methods Program participants were mailed a questionnaire to assess their satisfaction with the program so that we could determine the acceptability of video-teleconferencing for cancer risk assessment.

Results The overall level of satisfaction with the program was very high, demonstrating the acceptability of a cancer genetic risk assessment program that relied on telemedicine to reach and underserved minority community.

Limitations Delivery model requires the availability of and access to communication technologies; trained staff are needed at remote sites for sample collection and patient handling.

Conclusion Video-teleconferencing is an acceptable method of providing cancer risk assessment in a remote, underserved population.

Funding Supported primarily by a grant from the Cancer Prevention and Research Institute of Texas (PP120089 [GT]), NIH-NCI P30 CA54174 (CTRC at UTHSCSA); and a grant from the Valley Baptist Legacy Foundation. 

 

Click on the PDF icon at the top of this introduction to read the full article.

 

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Issue
The Journal of Community and Supportive Oncology - 14(4)
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Page Number
162-168
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genetic risk assessment, genetic counseling, breast cancer, colorectal cancer, telemedicine, video-conferencing, underserved population, Hispanic
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Background Breast and colorectal cancers are common cancers for which genetic risk assessment and counseling are available. However, these services are often limited to metropolitan areas and are not readily accessible to underserved populations. Moreover, ethnic and racial disparities present additional obstacles to identifying and screening high-risk individuals and have a bearing on treatment outcomes.

Objective To provide cancer genetic risk assessment and counseling through telemedicine to the remote, underserved primarily Hispanic population of the Texas-Mexico border region.

Methods Program participants were mailed a questionnaire to assess their satisfaction with the program so that we could determine the acceptability of video-teleconferencing for cancer risk assessment.

Results The overall level of satisfaction with the program was very high, demonstrating the acceptability of a cancer genetic risk assessment program that relied on telemedicine to reach and underserved minority community.

Limitations Delivery model requires the availability of and access to communication technologies; trained staff are needed at remote sites for sample collection and patient handling.

Conclusion Video-teleconferencing is an acceptable method of providing cancer risk assessment in a remote, underserved population.

Funding Supported primarily by a grant from the Cancer Prevention and Research Institute of Texas (PP120089 [GT]), NIH-NCI P30 CA54174 (CTRC at UTHSCSA); and a grant from the Valley Baptist Legacy Foundation. 

 

Click on the PDF icon at the top of this introduction to read the full article.

 

Background Breast and colorectal cancers are common cancers for which genetic risk assessment and counseling are available. However, these services are often limited to metropolitan areas and are not readily accessible to underserved populations. Moreover, ethnic and racial disparities present additional obstacles to identifying and screening high-risk individuals and have a bearing on treatment outcomes.

Objective To provide cancer genetic risk assessment and counseling through telemedicine to the remote, underserved primarily Hispanic population of the Texas-Mexico border region.

Methods Program participants were mailed a questionnaire to assess their satisfaction with the program so that we could determine the acceptability of video-teleconferencing for cancer risk assessment.

Results The overall level of satisfaction with the program was very high, demonstrating the acceptability of a cancer genetic risk assessment program that relied on telemedicine to reach and underserved minority community.

Limitations Delivery model requires the availability of and access to communication technologies; trained staff are needed at remote sites for sample collection and patient handling.

Conclusion Video-teleconferencing is an acceptable method of providing cancer risk assessment in a remote, underserved population.

Funding Supported primarily by a grant from the Cancer Prevention and Research Institute of Texas (PP120089 [GT]), NIH-NCI P30 CA54174 (CTRC at UTHSCSA); and a grant from the Valley Baptist Legacy Foundation. 

 

Click on the PDF icon at the top of this introduction to read the full article.

 

Issue
The Journal of Community and Supportive Oncology - 14(4)
Issue
The Journal of Community and Supportive Oncology - 14(4)
Page Number
162-168
Page Number
162-168
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Reaching high-risk underserved individuals for cancer genetic counseling by video-teleconferencing
Display Headline
Reaching high-risk underserved individuals for cancer genetic counseling by video-teleconferencing
Legacy Keywords
genetic risk assessment, genetic counseling, breast cancer, colorectal cancer, telemedicine, video-conferencing, underserved population, Hispanic
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genetic risk assessment, genetic counseling, breast cancer, colorectal cancer, telemedicine, video-conferencing, underserved population, Hispanic
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JCSO 2016;14:1162-168
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Diagnostic work-up for the detection of malnutrition in hospitalized cancer patients

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Diagnostic work-up for the detection of malnutrition in hospitalized cancer patients
Background Malnutrition is a common complication in patients suffering from cancer. It is associated with a poor prognosis, reduced quality of life, increased chemotherapy-induced toxicity, and a decreased response to therapy.

Objective To evaluate and compare the use of various diagnostic tests for the detection of malnutrition in patients hospitalized for cancer treatment.

Methods In this single-center, non-interventional reliability study, the nutritional status of 50 patients with cancer was assessed using the Nutritional Risk Screening (NRS-2002), a bioimpedance analysis (BIA), and the measurement of laboratory parameters that reflect the serum visceral protein level. For statistical analysis, the comparison of means and the agreement of the methods were calculated.

Results NRS-2002, BIA, and lab parameters differed widely among patients classified as well-nourished or malnourished (10%- 80%, depending on the method). Significant results in the comparison of means were observed for body mass index, serum protein, and some BIA parameters. The analysis of agreement identified a compelling agreement for pre-albumin and retinol-binding protein (RBP) (kappa = 0.81).

Limitations Small sample size, heterogeneous group of patients, non-interventional reliability study.

Conclusion The tested diagnostic methods for detecting malnutrition did not have an evident agreement among each other with a limited exchangeability. In routine hospital practice several methods should be applied in order to identify cancer patients at risk of malnutrition.

Funding/sponsorship Fresenius Kabi provided the BIA-unit and software. 

 

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The Journal of Community and Supportive Oncology - 14(4)
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155-161
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malnutrition, chemotherapy-induced toxicity, diagnostic test, serum visceral protein level
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Background Malnutrition is a common complication in patients suffering from cancer. It is associated with a poor prognosis, reduced quality of life, increased chemotherapy-induced toxicity, and a decreased response to therapy.

Objective To evaluate and compare the use of various diagnostic tests for the detection of malnutrition in patients hospitalized for cancer treatment.

Methods In this single-center, non-interventional reliability study, the nutritional status of 50 patients with cancer was assessed using the Nutritional Risk Screening (NRS-2002), a bioimpedance analysis (BIA), and the measurement of laboratory parameters that reflect the serum visceral protein level. For statistical analysis, the comparison of means and the agreement of the methods were calculated.

Results NRS-2002, BIA, and lab parameters differed widely among patients classified as well-nourished or malnourished (10%- 80%, depending on the method). Significant results in the comparison of means were observed for body mass index, serum protein, and some BIA parameters. The analysis of agreement identified a compelling agreement for pre-albumin and retinol-binding protein (RBP) (kappa = 0.81).

Limitations Small sample size, heterogeneous group of patients, non-interventional reliability study.

Conclusion The tested diagnostic methods for detecting malnutrition did not have an evident agreement among each other with a limited exchangeability. In routine hospital practice several methods should be applied in order to identify cancer patients at risk of malnutrition.

Funding/sponsorship Fresenius Kabi provided the BIA-unit and software. 

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

Background Malnutrition is a common complication in patients suffering from cancer. It is associated with a poor prognosis, reduced quality of life, increased chemotherapy-induced toxicity, and a decreased response to therapy.

Objective To evaluate and compare the use of various diagnostic tests for the detection of malnutrition in patients hospitalized for cancer treatment.

Methods In this single-center, non-interventional reliability study, the nutritional status of 50 patients with cancer was assessed using the Nutritional Risk Screening (NRS-2002), a bioimpedance analysis (BIA), and the measurement of laboratory parameters that reflect the serum visceral protein level. For statistical analysis, the comparison of means and the agreement of the methods were calculated.

Results NRS-2002, BIA, and lab parameters differed widely among patients classified as well-nourished or malnourished (10%- 80%, depending on the method). Significant results in the comparison of means were observed for body mass index, serum protein, and some BIA parameters. The analysis of agreement identified a compelling agreement for pre-albumin and retinol-binding protein (RBP) (kappa = 0.81).

Limitations Small sample size, heterogeneous group of patients, non-interventional reliability study.

Conclusion The tested diagnostic methods for detecting malnutrition did not have an evident agreement among each other with a limited exchangeability. In routine hospital practice several methods should be applied in order to identify cancer patients at risk of malnutrition.

Funding/sponsorship Fresenius Kabi provided the BIA-unit and software. 

 

Click on the PDF icon at the top of this introduction to read the full article. 

 

Issue
The Journal of Community and Supportive Oncology - 14(4)
Issue
The Journal of Community and Supportive Oncology - 14(4)
Page Number
155-161
Page Number
155-161
Publications
Publications
Topics
Article Type
Display Headline
Diagnostic work-up for the detection of malnutrition in hospitalized cancer patients
Display Headline
Diagnostic work-up for the detection of malnutrition in hospitalized cancer patients
Legacy Keywords
malnutrition, chemotherapy-induced toxicity, diagnostic test, serum visceral protein level
Legacy Keywords
malnutrition, chemotherapy-induced toxicity, diagnostic test, serum visceral protein level
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JCSO 2016;14:155-161
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