Clinical Edge Journal Scan

An ultrasound strategy for improving the prenatal detection of placenta accreta spectrum


 

Key clinical point: Ultrasound evaluation performed following a standardized protocol is highly effective at detecting placenta accreta spectrum (PAS) in pregnant women with persistent placenta previa under real-world conditions.

Main finding: Of 126 patients with placenta previa, PAS was detected in 11 patients, of which 10 were diagnosed prenatally by ultrasound, exhibiting a sensitivity of 90.9%, specificity of 98.3%, positive predictive value of 83.3%, and negative predictive value of 99.1%.

Study details: This was a retrospective real-world cohort study involving 126 pregnant women with persistent placenta previa who underwent standardized transabdominal and transvaginal ultrasound to assess hypoechoic retroplacental zone loss or myometrial thinning <1 mm, lacunar images (flow >15 cm/second), thick and bulging placenta, uterine-bladder serous interface thinning/interruption, and placental/uterovesical hypervascularity; the presence of at least 1 was considered high-risk for PAS.

Disclosures: The authors disclosed receiving no financial support for the study and having no conflict of interests.

Source: Juan-Clar M et al. Fetal Diagn Ther. 2022 (Jan 11). Doi: 10.1159/000521738.

Recommended Reading

Testing fetal structural anomalies using simultaneous CNV-seq and whole-exome sequencing
MDedge ObGyn
Combining ultrasound examination with NIPT improves positive predictive value for trisomy 18
MDedge ObGyn
Short femur length diagnosed in prenatal screening might require intensified pregnancy monitoring
MDedge ObGyn
Prenatal diagnosis of FGR with polyhydramnios is rare but with a high mortality rate
MDedge ObGyn
Singleton exome sequencing reveals disease-causing variants in fetuses with ultrasound anomalies
MDedge ObGyn
Risk factor-based screening inadequately discriminate parturients with and without elevated lead levels
MDedge ObGyn
Clinical Edge Journal Scan Commentary: Prenatal Testing February 2022
MDedge ObGyn
cfDNA screening for the common trisomies performs well in low-risk pregnancies
MDedge ObGyn
Fetuses with cerebral blood flow redistribution are susceptible to adverse perinatal outcomes
MDedge ObGyn
Prenatal diagnosis of neurocognitive disorders: Going beyond what’s currently indicated
MDedge ObGyn