Improving Healthcare Value: Effectiveness of a Program to Reduce Laboratory Testing for Non-Critically-Ill Patients With COVID-19

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Improving Healthcare Value: Effectiveness of a Program to Reduce Laboratory Testing for Non-Critically-Ill Patients With COVID-19

The COVID-19 pandemic posed an unprecedented challenge to our current healthcare system—how to efficiently develop and standardize care for a disease process yet to be fully characterized while continuing to deliver high-value care. In the United States, many local institutions developed their own practice patterns, resulting in wide variation.

The Society of Hospital Medicine’s Choosing Wisely® recommendations include avoiding repetitive routine laboratory testing.1In the setting of the early stages of the COVID-19 pandemic (particularly before vaccines were broadly available), the benefits of avoiding routine repetitive testing may have been more pronounced considering the need to limit unnecessary healthcare professional exposure to infected individuals and to conserve resources, including personal protective equipment (PPE) and laboratory resources.2

In April 2020, at Dell Seton Medical Center (DSMC) at the University of Texas at Austin, we created a Therapeutics and Informatics Committee to critically review evidence-based practices, reach consensus, and guide practice patterns, with the aim of delivering high-value care. This brief report aims to evaluate the effectiveness of standardized electronic health record (EHR) order sets in appropriately decreasing lab testing for non-critically-ill hospitalized COVID-19 patients.

METHODS

Study Design and Setting

We followed SQUIRE guidelines for reporting this quality improvement intervention.3 Using retrospective chart review, we analyzed laboratory ordering patterns for COVID-positive patients at a single safety net academic medical center in Austin, Texas. Data were abstracted using a custom SQL query of our EHR and de-identified for this analysis. Our internal review board determined that this project is a quality improvement project and did not meet the criteria of human subjects research.

Study Population

All adult (age ≥18 years), non-intensive care unit (ICU), COVID-positive patients with an observation or inpatient status discharged between March 30, 2020, and March 7, 2021, were included in the analysis. Patients were excluded if they were ever transferred to an ICU. COVID-positive status was confirmed via a positive polymerase chain reaction (PCR) test for SARS-CoV-2.

Intervention

In April 2020, we created a Therapeutics and Informatics Committee, an interprofessional group including hospitalists, infectious disease, pulmonary and critical care, pharmacy, hospital leadership, and other subspecialists, to iteratively evaluate evidence and standardize inpatient care. This committee was created in response to the COVID-19 pandemic and has been uniquely focused on COVID-19-related care.

On April 30, 2020, the committee met to evaluate routine laboratory tests in patients with COVID-19. Prior to this meeting, there was a clinical order set (Cerner “powerplan”) in the EHR that included daily laboratory tests, and individual provider ordering practices were heterogeneous, with a strong predilection for ordering an array of inflammatory markers with unclear clinical benefit and high cost. The committee’s consensus recommendation at that meeting was that patients admitted to the floor did not require routine daily laboratory tests. Complete blood count (CBC), complete metabolic panel (CMP), D-dimer, and troponin were among the labs recommended to be obtained no more frequently than every other day. The committee believed that reducing unnecessary labs would improve value without compromising patient care. These lab ordering practices were incorporated into a customized COVID-19 EHR order set that could be shared among providers, but are not discoverable using the search feature until they are formally built by the informatics team. Changes to the order sets were communicated through multiple platforms and widely adopted by frontline providers.

The committee revisited laboratory ordering practices on June 25, 2020, making the recommendation to further discontinue trending troponin levels and reduce the amount of baseline labs, as they were contributing little to the clinical gestalt or changing management decisions. The customized EHR order sets were updated to reflect the new recommendations, and providers were encouraged to adopt them.

Although direct feedback on ordering practices can be an effective component of a multipronged intervention for decreasing lab usage,4 in this particular case we did not provide feedback to physicians related to their lab usage for COVID-19 care. We provided education to all physicians following each local COVID management consensus guideline change through email, handbook-style updates, and occasional conferences.

Measures and Analysis

The main process measure for this study was the mean hospitalization-level proportion of calendar hospital days with at least one laboratory result for each of four separate lab types: white blood cell count (WBC, as a marker for CBC), creatinine (as a marker for chemistry panels), troponin-I, and D-dimer. First, individual hospitalization-level proportions were calculated for each patient and each lab type. For example, if a patient with a length of stay of 5 calendar days had a WBC measured 2 of those days, their WBC proportion was 0.4. Then we calculated the mean of these proportions for all patients discharged in a given week during the study period for each lab type. Using this measure allowed us to understand the cadence of lab ordering and whether labs were checked daily.

Mean daily lab proportions were plotted separately for CBC, chemistry panel, troponin I, and D-dimer on statistical process control (SPC) charts. The baseline period used for all SPC charts included the calendar weeks March 30, 2020, through June 1, 2020. The Montgomery rules were used for determining periods of special cause variation.

RESULTS

A total of 1,402 non-ICU COVID-positive patients were discharged between March 30, 2020, and March 7, 2021, from our hospital, with a median length of stay of 3.00 days (weekly discharge data are shown in the Figure). The majority of patients were Hispanic men, with a mean age of 54 years (Appendix Table).

Statistical Process Control Charts of Lab Usage Over Time for Non-Critically Ill COVID-19 Inpatients

To assess intervention fidelity of the order sets, we performed two random spot checks (on May 15, 2020, and June 2, 2020) and found that 16/18 (89%) and 21/25 (84%) of COVID admissions had used the customized order set, supporting robust uptake of the order set intervention.

Mean daily lab proportions for each of the four lab types—chemistry panels, CBCs, D-dimer, and troponin—all demonstrated special cause variation starting mid June to early July 2020 (Figure). All four charts demonstrated periods of four points below 1-sigma and eight points below the center line, with troponin and D-dimer also demonstrating periods of two points below 2-sigma and one point below the lower control limit. These periods of special cause variation were sustained through February 2021. This represents a significant increase in the number of days that these hospitalized patients did not have these labs drawn.

We evaluated the proportion of all COVID-19 patients who spent time in the ICU over the entire study period, which remained consistent at approximately 25% of our hospitalized COVID-19 population. On a SPC chart, there was no evidence of change in ICU patients following our intervention.

DISCUSSION

Non-critically-ill COVID-19 patients at our hospital had more inpatient days where they did not receive specific laboratory tests following the introduction of locally developed, standardized recommendations and an electronic order set. These data show sustainability and endurance of this intervention through both our summer and winter surges, and the association did not correlate directly with significant changes in the number of COVID-19 patient discharges, supporting that its impact is independent of case volume.

Whereas Choosing Wisely® recommendations have been traditionally based on well-established common areas of overuse, this example is unique in showing how these same underlying principles can be applied even in unclear situations, such as with the COVID-19 pandemic. Through multidisciplinary review of real-time evidence and accumulating local experience, the Therapeutics and Informatics Committee at our hospital was able to reach consensus and rapidly deploy an electronic order set that was widely adopted. Eventually, the order set was formally adopted into our EHR; however, the customized COVID-19 order set allowed rapid improvement and implementation of changes that could be shared among providers. As confirmed by our spot checks, this order set was widely used. The order set bolstered the effect of our Therapeutics and Informatics Committee, which served as our platform to disseminate consensus recommendations and build them into clinical workflows.

There are several limitations to this brief analysis. First, we were unable to assess patient outcomes in response to these changes, mostly due to multiple confounding variables throughout this time period with rapidly shifting census numbers, and the adoption of therapeutic interventions, such as the introduction of dexamethasone, which has shown a mortality benefit for patients with COVID-19. However, we have no reason to believe that this decrease in routine laboratory ordering was associated with adverse outcomes for our patients, and, in aggregate, the outcomes (eg, mortality, length of stay, readmissions) for COVID-19 patients at our hospital have been better than average across Vizient peer groups.6 Prior studies have shown that reduced inpatient labs do not have an adverse impact on patient outcomes.7 Furthermore, non-ICU COVID-19 is generally a single-organ disease (unlike patients with critical illness from COVID-19), making it more likely that daily labs are unnecessary in this specific patient population. There was no increase in the proportion of COVID-19 ICU patients following our intervention.

In conclusion, the principles of Choosing Wisely® can be applied even within novel and quickly evolving situations, relying on rapid and critical review of evidence, clinician consensus-building, and leveraging available interventions to drive behavior change, such as shared order sets.

Files
References

1. Bulger J, Nickel W, Messler J, et al. Choosing wisely in adult hospital medicine: five opportunities for improved healthcare value. J Hosp Med. 2013;8(9):486-492. https://doi.org/10.1002/jhm.2063
2. Emanuel EJ, Persad G, Upshur R, et al. Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med. 2020;382(21):2049-2055. https://doi.org/10.1056/NEJMsb2005114
3. Ogrinc G, Davies L, Goodman D, Batalden P, Davidoff F, Stevens D. SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process. BMJ Qual Saf. 2016;25(12):986-992. https://doi.org/10.1136/bmjqs-2015-004411
4. Wheeler D, Marcus P, Nguyen J, et al. Evaluation of a resident-led project to decrease phlebotomy rates in the hospital: think twice, stick once. JAMA Intern Med. 2016;176(5):708-710. https://doi.org/10.1001/jamainternmed.2016.0549
5. Montgomery DC. Introduction to Statistical Quality Control. 6th ed. Wiley; 2008.
6. Nieto K, Pierce RG, Moriates C, Schulwolf E. Lessons from the pandemic: building COVID-19 Centers of Excellence. The Hospital Leader - The Official Blog of the Society of Hospital Medicine. October 13, 2020. Accessed December 11, 2020. https://thehospitalleader.org/lessons-from-the-pandemic-building-covid-19-centers-of-excellence/
7. Corson AH, Fan VS, White T, et al. A multifaceted hospitalist quality improvement intervention: decreased frequency of common labs. J Hosp Med. 2015;10(6):390-395. https://doi.org/10.1002/jhm.2354

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1Department of Internal Medicine, Dell Medical School at The University of Texas at Austin; 2Costs of Care, Boston, Massachusetts.

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The COVID-19 pandemic posed an unprecedented challenge to our current healthcare system—how to efficiently develop and standardize care for a disease process yet to be fully characterized while continuing to deliver high-value care. In the United States, many local institutions developed their own practice patterns, resulting in wide variation.

The Society of Hospital Medicine’s Choosing Wisely® recommendations include avoiding repetitive routine laboratory testing.1In the setting of the early stages of the COVID-19 pandemic (particularly before vaccines were broadly available), the benefits of avoiding routine repetitive testing may have been more pronounced considering the need to limit unnecessary healthcare professional exposure to infected individuals and to conserve resources, including personal protective equipment (PPE) and laboratory resources.2

In April 2020, at Dell Seton Medical Center (DSMC) at the University of Texas at Austin, we created a Therapeutics and Informatics Committee to critically review evidence-based practices, reach consensus, and guide practice patterns, with the aim of delivering high-value care. This brief report aims to evaluate the effectiveness of standardized electronic health record (EHR) order sets in appropriately decreasing lab testing for non-critically-ill hospitalized COVID-19 patients.

METHODS

Study Design and Setting

We followed SQUIRE guidelines for reporting this quality improvement intervention.3 Using retrospective chart review, we analyzed laboratory ordering patterns for COVID-positive patients at a single safety net academic medical center in Austin, Texas. Data were abstracted using a custom SQL query of our EHR and de-identified for this analysis. Our internal review board determined that this project is a quality improvement project and did not meet the criteria of human subjects research.

Study Population

All adult (age ≥18 years), non-intensive care unit (ICU), COVID-positive patients with an observation or inpatient status discharged between March 30, 2020, and March 7, 2021, were included in the analysis. Patients were excluded if they were ever transferred to an ICU. COVID-positive status was confirmed via a positive polymerase chain reaction (PCR) test for SARS-CoV-2.

Intervention

In April 2020, we created a Therapeutics and Informatics Committee, an interprofessional group including hospitalists, infectious disease, pulmonary and critical care, pharmacy, hospital leadership, and other subspecialists, to iteratively evaluate evidence and standardize inpatient care. This committee was created in response to the COVID-19 pandemic and has been uniquely focused on COVID-19-related care.

On April 30, 2020, the committee met to evaluate routine laboratory tests in patients with COVID-19. Prior to this meeting, there was a clinical order set (Cerner “powerplan”) in the EHR that included daily laboratory tests, and individual provider ordering practices were heterogeneous, with a strong predilection for ordering an array of inflammatory markers with unclear clinical benefit and high cost. The committee’s consensus recommendation at that meeting was that patients admitted to the floor did not require routine daily laboratory tests. Complete blood count (CBC), complete metabolic panel (CMP), D-dimer, and troponin were among the labs recommended to be obtained no more frequently than every other day. The committee believed that reducing unnecessary labs would improve value without compromising patient care. These lab ordering practices were incorporated into a customized COVID-19 EHR order set that could be shared among providers, but are not discoverable using the search feature until they are formally built by the informatics team. Changes to the order sets were communicated through multiple platforms and widely adopted by frontline providers.

The committee revisited laboratory ordering practices on June 25, 2020, making the recommendation to further discontinue trending troponin levels and reduce the amount of baseline labs, as they were contributing little to the clinical gestalt or changing management decisions. The customized EHR order sets were updated to reflect the new recommendations, and providers were encouraged to adopt them.

Although direct feedback on ordering practices can be an effective component of a multipronged intervention for decreasing lab usage,4 in this particular case we did not provide feedback to physicians related to their lab usage for COVID-19 care. We provided education to all physicians following each local COVID management consensus guideline change through email, handbook-style updates, and occasional conferences.

Measures and Analysis

The main process measure for this study was the mean hospitalization-level proportion of calendar hospital days with at least one laboratory result for each of four separate lab types: white blood cell count (WBC, as a marker for CBC), creatinine (as a marker for chemistry panels), troponin-I, and D-dimer. First, individual hospitalization-level proportions were calculated for each patient and each lab type. For example, if a patient with a length of stay of 5 calendar days had a WBC measured 2 of those days, their WBC proportion was 0.4. Then we calculated the mean of these proportions for all patients discharged in a given week during the study period for each lab type. Using this measure allowed us to understand the cadence of lab ordering and whether labs were checked daily.

Mean daily lab proportions were plotted separately for CBC, chemistry panel, troponin I, and D-dimer on statistical process control (SPC) charts. The baseline period used for all SPC charts included the calendar weeks March 30, 2020, through June 1, 2020. The Montgomery rules were used for determining periods of special cause variation.

RESULTS

A total of 1,402 non-ICU COVID-positive patients were discharged between March 30, 2020, and March 7, 2021, from our hospital, with a median length of stay of 3.00 days (weekly discharge data are shown in the Figure). The majority of patients were Hispanic men, with a mean age of 54 years (Appendix Table).

Statistical Process Control Charts of Lab Usage Over Time for Non-Critically Ill COVID-19 Inpatients

To assess intervention fidelity of the order sets, we performed two random spot checks (on May 15, 2020, and June 2, 2020) and found that 16/18 (89%) and 21/25 (84%) of COVID admissions had used the customized order set, supporting robust uptake of the order set intervention.

Mean daily lab proportions for each of the four lab types—chemistry panels, CBCs, D-dimer, and troponin—all demonstrated special cause variation starting mid June to early July 2020 (Figure). All four charts demonstrated periods of four points below 1-sigma and eight points below the center line, with troponin and D-dimer also demonstrating periods of two points below 2-sigma and one point below the lower control limit. These periods of special cause variation were sustained through February 2021. This represents a significant increase in the number of days that these hospitalized patients did not have these labs drawn.

We evaluated the proportion of all COVID-19 patients who spent time in the ICU over the entire study period, which remained consistent at approximately 25% of our hospitalized COVID-19 population. On a SPC chart, there was no evidence of change in ICU patients following our intervention.

DISCUSSION

Non-critically-ill COVID-19 patients at our hospital had more inpatient days where they did not receive specific laboratory tests following the introduction of locally developed, standardized recommendations and an electronic order set. These data show sustainability and endurance of this intervention through both our summer and winter surges, and the association did not correlate directly with significant changes in the number of COVID-19 patient discharges, supporting that its impact is independent of case volume.

Whereas Choosing Wisely® recommendations have been traditionally based on well-established common areas of overuse, this example is unique in showing how these same underlying principles can be applied even in unclear situations, such as with the COVID-19 pandemic. Through multidisciplinary review of real-time evidence and accumulating local experience, the Therapeutics and Informatics Committee at our hospital was able to reach consensus and rapidly deploy an electronic order set that was widely adopted. Eventually, the order set was formally adopted into our EHR; however, the customized COVID-19 order set allowed rapid improvement and implementation of changes that could be shared among providers. As confirmed by our spot checks, this order set was widely used. The order set bolstered the effect of our Therapeutics and Informatics Committee, which served as our platform to disseminate consensus recommendations and build them into clinical workflows.

There are several limitations to this brief analysis. First, we were unable to assess patient outcomes in response to these changes, mostly due to multiple confounding variables throughout this time period with rapidly shifting census numbers, and the adoption of therapeutic interventions, such as the introduction of dexamethasone, which has shown a mortality benefit for patients with COVID-19. However, we have no reason to believe that this decrease in routine laboratory ordering was associated with adverse outcomes for our patients, and, in aggregate, the outcomes (eg, mortality, length of stay, readmissions) for COVID-19 patients at our hospital have been better than average across Vizient peer groups.6 Prior studies have shown that reduced inpatient labs do not have an adverse impact on patient outcomes.7 Furthermore, non-ICU COVID-19 is generally a single-organ disease (unlike patients with critical illness from COVID-19), making it more likely that daily labs are unnecessary in this specific patient population. There was no increase in the proportion of COVID-19 ICU patients following our intervention.

In conclusion, the principles of Choosing Wisely® can be applied even within novel and quickly evolving situations, relying on rapid and critical review of evidence, clinician consensus-building, and leveraging available interventions to drive behavior change, such as shared order sets.

The COVID-19 pandemic posed an unprecedented challenge to our current healthcare system—how to efficiently develop and standardize care for a disease process yet to be fully characterized while continuing to deliver high-value care. In the United States, many local institutions developed their own practice patterns, resulting in wide variation.

The Society of Hospital Medicine’s Choosing Wisely® recommendations include avoiding repetitive routine laboratory testing.1In the setting of the early stages of the COVID-19 pandemic (particularly before vaccines were broadly available), the benefits of avoiding routine repetitive testing may have been more pronounced considering the need to limit unnecessary healthcare professional exposure to infected individuals and to conserve resources, including personal protective equipment (PPE) and laboratory resources.2

In April 2020, at Dell Seton Medical Center (DSMC) at the University of Texas at Austin, we created a Therapeutics and Informatics Committee to critically review evidence-based practices, reach consensus, and guide practice patterns, with the aim of delivering high-value care. This brief report aims to evaluate the effectiveness of standardized electronic health record (EHR) order sets in appropriately decreasing lab testing for non-critically-ill hospitalized COVID-19 patients.

METHODS

Study Design and Setting

We followed SQUIRE guidelines for reporting this quality improvement intervention.3 Using retrospective chart review, we analyzed laboratory ordering patterns for COVID-positive patients at a single safety net academic medical center in Austin, Texas. Data were abstracted using a custom SQL query of our EHR and de-identified for this analysis. Our internal review board determined that this project is a quality improvement project and did not meet the criteria of human subjects research.

Study Population

All adult (age ≥18 years), non-intensive care unit (ICU), COVID-positive patients with an observation or inpatient status discharged between March 30, 2020, and March 7, 2021, were included in the analysis. Patients were excluded if they were ever transferred to an ICU. COVID-positive status was confirmed via a positive polymerase chain reaction (PCR) test for SARS-CoV-2.

Intervention

In April 2020, we created a Therapeutics and Informatics Committee, an interprofessional group including hospitalists, infectious disease, pulmonary and critical care, pharmacy, hospital leadership, and other subspecialists, to iteratively evaluate evidence and standardize inpatient care. This committee was created in response to the COVID-19 pandemic and has been uniquely focused on COVID-19-related care.

On April 30, 2020, the committee met to evaluate routine laboratory tests in patients with COVID-19. Prior to this meeting, there was a clinical order set (Cerner “powerplan”) in the EHR that included daily laboratory tests, and individual provider ordering practices were heterogeneous, with a strong predilection for ordering an array of inflammatory markers with unclear clinical benefit and high cost. The committee’s consensus recommendation at that meeting was that patients admitted to the floor did not require routine daily laboratory tests. Complete blood count (CBC), complete metabolic panel (CMP), D-dimer, and troponin were among the labs recommended to be obtained no more frequently than every other day. The committee believed that reducing unnecessary labs would improve value without compromising patient care. These lab ordering practices were incorporated into a customized COVID-19 EHR order set that could be shared among providers, but are not discoverable using the search feature until they are formally built by the informatics team. Changes to the order sets were communicated through multiple platforms and widely adopted by frontline providers.

The committee revisited laboratory ordering practices on June 25, 2020, making the recommendation to further discontinue trending troponin levels and reduce the amount of baseline labs, as they were contributing little to the clinical gestalt or changing management decisions. The customized EHR order sets were updated to reflect the new recommendations, and providers were encouraged to adopt them.

Although direct feedback on ordering practices can be an effective component of a multipronged intervention for decreasing lab usage,4 in this particular case we did not provide feedback to physicians related to their lab usage for COVID-19 care. We provided education to all physicians following each local COVID management consensus guideline change through email, handbook-style updates, and occasional conferences.

Measures and Analysis

The main process measure for this study was the mean hospitalization-level proportion of calendar hospital days with at least one laboratory result for each of four separate lab types: white blood cell count (WBC, as a marker for CBC), creatinine (as a marker for chemistry panels), troponin-I, and D-dimer. First, individual hospitalization-level proportions were calculated for each patient and each lab type. For example, if a patient with a length of stay of 5 calendar days had a WBC measured 2 of those days, their WBC proportion was 0.4. Then we calculated the mean of these proportions for all patients discharged in a given week during the study period for each lab type. Using this measure allowed us to understand the cadence of lab ordering and whether labs were checked daily.

Mean daily lab proportions were plotted separately for CBC, chemistry panel, troponin I, and D-dimer on statistical process control (SPC) charts. The baseline period used for all SPC charts included the calendar weeks March 30, 2020, through June 1, 2020. The Montgomery rules were used for determining periods of special cause variation.

RESULTS

A total of 1,402 non-ICU COVID-positive patients were discharged between March 30, 2020, and March 7, 2021, from our hospital, with a median length of stay of 3.00 days (weekly discharge data are shown in the Figure). The majority of patients were Hispanic men, with a mean age of 54 years (Appendix Table).

Statistical Process Control Charts of Lab Usage Over Time for Non-Critically Ill COVID-19 Inpatients

To assess intervention fidelity of the order sets, we performed two random spot checks (on May 15, 2020, and June 2, 2020) and found that 16/18 (89%) and 21/25 (84%) of COVID admissions had used the customized order set, supporting robust uptake of the order set intervention.

Mean daily lab proportions for each of the four lab types—chemistry panels, CBCs, D-dimer, and troponin—all demonstrated special cause variation starting mid June to early July 2020 (Figure). All four charts demonstrated periods of four points below 1-sigma and eight points below the center line, with troponin and D-dimer also demonstrating periods of two points below 2-sigma and one point below the lower control limit. These periods of special cause variation were sustained through February 2021. This represents a significant increase in the number of days that these hospitalized patients did not have these labs drawn.

We evaluated the proportion of all COVID-19 patients who spent time in the ICU over the entire study period, which remained consistent at approximately 25% of our hospitalized COVID-19 population. On a SPC chart, there was no evidence of change in ICU patients following our intervention.

DISCUSSION

Non-critically-ill COVID-19 patients at our hospital had more inpatient days where they did not receive specific laboratory tests following the introduction of locally developed, standardized recommendations and an electronic order set. These data show sustainability and endurance of this intervention through both our summer and winter surges, and the association did not correlate directly with significant changes in the number of COVID-19 patient discharges, supporting that its impact is independent of case volume.

Whereas Choosing Wisely® recommendations have been traditionally based on well-established common areas of overuse, this example is unique in showing how these same underlying principles can be applied even in unclear situations, such as with the COVID-19 pandemic. Through multidisciplinary review of real-time evidence and accumulating local experience, the Therapeutics and Informatics Committee at our hospital was able to reach consensus and rapidly deploy an electronic order set that was widely adopted. Eventually, the order set was formally adopted into our EHR; however, the customized COVID-19 order set allowed rapid improvement and implementation of changes that could be shared among providers. As confirmed by our spot checks, this order set was widely used. The order set bolstered the effect of our Therapeutics and Informatics Committee, which served as our platform to disseminate consensus recommendations and build them into clinical workflows.

There are several limitations to this brief analysis. First, we were unable to assess patient outcomes in response to these changes, mostly due to multiple confounding variables throughout this time period with rapidly shifting census numbers, and the adoption of therapeutic interventions, such as the introduction of dexamethasone, which has shown a mortality benefit for patients with COVID-19. However, we have no reason to believe that this decrease in routine laboratory ordering was associated with adverse outcomes for our patients, and, in aggregate, the outcomes (eg, mortality, length of stay, readmissions) for COVID-19 patients at our hospital have been better than average across Vizient peer groups.6 Prior studies have shown that reduced inpatient labs do not have an adverse impact on patient outcomes.7 Furthermore, non-ICU COVID-19 is generally a single-organ disease (unlike patients with critical illness from COVID-19), making it more likely that daily labs are unnecessary in this specific patient population. There was no increase in the proportion of COVID-19 ICU patients following our intervention.

In conclusion, the principles of Choosing Wisely® can be applied even within novel and quickly evolving situations, relying on rapid and critical review of evidence, clinician consensus-building, and leveraging available interventions to drive behavior change, such as shared order sets.

References

1. Bulger J, Nickel W, Messler J, et al. Choosing wisely in adult hospital medicine: five opportunities for improved healthcare value. J Hosp Med. 2013;8(9):486-492. https://doi.org/10.1002/jhm.2063
2. Emanuel EJ, Persad G, Upshur R, et al. Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med. 2020;382(21):2049-2055. https://doi.org/10.1056/NEJMsb2005114
3. Ogrinc G, Davies L, Goodman D, Batalden P, Davidoff F, Stevens D. SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process. BMJ Qual Saf. 2016;25(12):986-992. https://doi.org/10.1136/bmjqs-2015-004411
4. Wheeler D, Marcus P, Nguyen J, et al. Evaluation of a resident-led project to decrease phlebotomy rates in the hospital: think twice, stick once. JAMA Intern Med. 2016;176(5):708-710. https://doi.org/10.1001/jamainternmed.2016.0549
5. Montgomery DC. Introduction to Statistical Quality Control. 6th ed. Wiley; 2008.
6. Nieto K, Pierce RG, Moriates C, Schulwolf E. Lessons from the pandemic: building COVID-19 Centers of Excellence. The Hospital Leader - The Official Blog of the Society of Hospital Medicine. October 13, 2020. Accessed December 11, 2020. https://thehospitalleader.org/lessons-from-the-pandemic-building-covid-19-centers-of-excellence/
7. Corson AH, Fan VS, White T, et al. A multifaceted hospitalist quality improvement intervention: decreased frequency of common labs. J Hosp Med. 2015;10(6):390-395. https://doi.org/10.1002/jhm.2354

References

1. Bulger J, Nickel W, Messler J, et al. Choosing wisely in adult hospital medicine: five opportunities for improved healthcare value. J Hosp Med. 2013;8(9):486-492. https://doi.org/10.1002/jhm.2063
2. Emanuel EJ, Persad G, Upshur R, et al. Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med. 2020;382(21):2049-2055. https://doi.org/10.1056/NEJMsb2005114
3. Ogrinc G, Davies L, Goodman D, Batalden P, Davidoff F, Stevens D. SQUIRE 2.0 (Standards for QUality Improvement Reporting Excellence): revised publication guidelines from a detailed consensus process. BMJ Qual Saf. 2016;25(12):986-992. https://doi.org/10.1136/bmjqs-2015-004411
4. Wheeler D, Marcus P, Nguyen J, et al. Evaluation of a resident-led project to decrease phlebotomy rates in the hospital: think twice, stick once. JAMA Intern Med. 2016;176(5):708-710. https://doi.org/10.1001/jamainternmed.2016.0549
5. Montgomery DC. Introduction to Statistical Quality Control. 6th ed. Wiley; 2008.
6. Nieto K, Pierce RG, Moriates C, Schulwolf E. Lessons from the pandemic: building COVID-19 Centers of Excellence. The Hospital Leader - The Official Blog of the Society of Hospital Medicine. October 13, 2020. Accessed December 11, 2020. https://thehospitalleader.org/lessons-from-the-pandemic-building-covid-19-centers-of-excellence/
7. Corson AH, Fan VS, White T, et al. A multifaceted hospitalist quality improvement intervention: decreased frequency of common labs. J Hosp Med. 2015;10(6):390-395. https://doi.org/10.1002/jhm.2354

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Patients dying without their loved ones, families forced to remotely decide goals of care without the physical presence or human connection of the care team, overworked staff physically isolated from their critically ill patients, and at-risk community members with uncertain and undocumented goals for care are among the universal challenges confronted by hospitals and hospitalists during this COVID-19 pandemic. Partnerships among hospital medicine (HM) and palliative care (PC) teams at Dell Medical School/Dell Seton Medical Center thrive on mutually shared core values of patient centered care – compassion, empathy, and humanity.

A key PC-HM collaboration was adapting our multidisciplinary huddle to focus on communication effectiveness and efficiency in the medical intensive care unit (MICU). Expanded interprofessional and cross-specialty collaboration promoted streamlined, succinct, and standardized communication with patients’ families while their loved ones were critically ill with COVID-19. The PC team attended daily MICU multidisciplinary huddles, attentive to both the medical and psychosocial updates for each patient. During huddles, residents or HM providers were asked to end their presentation with a clinical status “headline” and solicited feedback from the multidisciplinary team before messaging to the family. The PC team then communicated with families a succinct and cohesive medical update and continuously explored goals of care. This allowed the HM team, often overwhelmed with admissions, co-managing intensive care patients, and facilitating safe discharges, to focus on urgent issues while PC provided continuity and personalized support for patients and families. PC’s ability to synthesize and summarize clinical information from multiple teams and then provide cohesive updates in patient-friendly language modeled important communication skills for learners and simultaneously benefited HM providers.

Our chaplains, too, were central to facilitating timely, proactive conversations and documentation of Medical Power of Attorney (MPOA) for patients with COVID-19 admitted to our hospital. HM prioritized early admission conversations with patients to counsel them on severity of illness, prognosis based on risk factors, to elucidate wishes for intubation or resuscitation, and to capture their desired medical decision maker. HM was notified of all COVID and PUI admissions, allowing us to speak with even critically ill patients in the ER or ICU prior to intubation in order to quickly and accurately capture patients’ wishes for treatment and delegate decision makers. Our chaplains supported and supplemented these efforts by diligently and dutifully soliciting, hearing, and documenting patient MPOA delegates, with over 50% MPOA completion by 24 hours of hospitalization.

Another early PC-HM project, “Meet My Loved One,” was adapted from the University of Alabama at Birmingham Palliative and Comfort Unit. The absence of families visiting the ICU and sharing pictures, stories, anecdotes of our patients left a deeply felt, dehumanizing void in the halls and rooms of our hospital. To fill this space with life and humanity, furloughed medical students on their “transition of care” electives contacted family members of their “continuity” patients focusing primarily on those patients expected to have prolonged ICU or hospital stays and solicited personal, humanizing information about our patients. Questions included: “What is your loved one’s preferred name or nickname?” and “What are three things we should know to take better care of your loved one?” With family permission, we posted this information on the door outside the patient’s room. Nursing staff, in particular, appreciated getting to know their patients more personally and families appreciated the staff’s desire to know their loved one as an individual.

It is also important to acknowledge setbacks. Early efforts to engage technology proved more foe than friend. We continue to struggle with using our iPads for video visits. Most of our families prefer “WhatsApp” for video communication, which is not compatible with operating systems on early versions of the iPad, which were generously and widely donated by local school systems. Desperate to allow families to connect, many providers resorted to using personal devices to facilitate video visits and family meetings. And we discovered that many video visits caused more not less family angst, especially for critically ill patients. Families often required preparation and coaching on what to expect and how to interact with intubated, sedated, proned, and paralyzed loved ones.

Our hospital medicine and palliative care teams have an established strong partnership. The COVID-19 pandemic created novel communication challenges but our shared mission toward patient-centered care allowed us to effectively collaborate to bring the patients goals of care to the forefront aligning patients, families, physicians, nurses, and staff during the COVID-19 surge.

Dr. Johnston is associate professor at Dell Medical School at The University of Texas in Austin. She practices hospital medicine and inpatient palliative care at Dell Seton Medical Center. Dr. Cooremans is a resident physician at Dell Medical School. Dr. Salib is the internal medicine clerkship director and an associate professor at Dell Medical School. Dr. Nieto is an assistant professor and associate chief of the Division of Hospital Medicine at Dell Medical School. Dr. Patel is an assistant professor at Dell Medical School. This article is part of a series written by members of the Division of Hospital Medicine at Dell Medical School, exploring lessons learned from the coronavirus pandemic and outlining an approach for creating COVID-19 Centers of Excellence. The article first appeared in The Hospital Leader, the official blog of SHM.

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Patients dying without their loved ones, families forced to remotely decide goals of care without the physical presence or human connection of the care team, overworked staff physically isolated from their critically ill patients, and at-risk community members with uncertain and undocumented goals for care are among the universal challenges confronted by hospitals and hospitalists during this COVID-19 pandemic. Partnerships among hospital medicine (HM) and palliative care (PC) teams at Dell Medical School/Dell Seton Medical Center thrive on mutually shared core values of patient centered care – compassion, empathy, and humanity.

A key PC-HM collaboration was adapting our multidisciplinary huddle to focus on communication effectiveness and efficiency in the medical intensive care unit (MICU). Expanded interprofessional and cross-specialty collaboration promoted streamlined, succinct, and standardized communication with patients’ families while their loved ones were critically ill with COVID-19. The PC team attended daily MICU multidisciplinary huddles, attentive to both the medical and psychosocial updates for each patient. During huddles, residents or HM providers were asked to end their presentation with a clinical status “headline” and solicited feedback from the multidisciplinary team before messaging to the family. The PC team then communicated with families a succinct and cohesive medical update and continuously explored goals of care. This allowed the HM team, often overwhelmed with admissions, co-managing intensive care patients, and facilitating safe discharges, to focus on urgent issues while PC provided continuity and personalized support for patients and families. PC’s ability to synthesize and summarize clinical information from multiple teams and then provide cohesive updates in patient-friendly language modeled important communication skills for learners and simultaneously benefited HM providers.

Our chaplains, too, were central to facilitating timely, proactive conversations and documentation of Medical Power of Attorney (MPOA) for patients with COVID-19 admitted to our hospital. HM prioritized early admission conversations with patients to counsel them on severity of illness, prognosis based on risk factors, to elucidate wishes for intubation or resuscitation, and to capture their desired medical decision maker. HM was notified of all COVID and PUI admissions, allowing us to speak with even critically ill patients in the ER or ICU prior to intubation in order to quickly and accurately capture patients’ wishes for treatment and delegate decision makers. Our chaplains supported and supplemented these efforts by diligently and dutifully soliciting, hearing, and documenting patient MPOA delegates, with over 50% MPOA completion by 24 hours of hospitalization.

Another early PC-HM project, “Meet My Loved One,” was adapted from the University of Alabama at Birmingham Palliative and Comfort Unit. The absence of families visiting the ICU and sharing pictures, stories, anecdotes of our patients left a deeply felt, dehumanizing void in the halls and rooms of our hospital. To fill this space with life and humanity, furloughed medical students on their “transition of care” electives contacted family members of their “continuity” patients focusing primarily on those patients expected to have prolonged ICU or hospital stays and solicited personal, humanizing information about our patients. Questions included: “What is your loved one’s preferred name or nickname?” and “What are three things we should know to take better care of your loved one?” With family permission, we posted this information on the door outside the patient’s room. Nursing staff, in particular, appreciated getting to know their patients more personally and families appreciated the staff’s desire to know their loved one as an individual.

It is also important to acknowledge setbacks. Early efforts to engage technology proved more foe than friend. We continue to struggle with using our iPads for video visits. Most of our families prefer “WhatsApp” for video communication, which is not compatible with operating systems on early versions of the iPad, which were generously and widely donated by local school systems. Desperate to allow families to connect, many providers resorted to using personal devices to facilitate video visits and family meetings. And we discovered that many video visits caused more not less family angst, especially for critically ill patients. Families often required preparation and coaching on what to expect and how to interact with intubated, sedated, proned, and paralyzed loved ones.

Our hospital medicine and palliative care teams have an established strong partnership. The COVID-19 pandemic created novel communication challenges but our shared mission toward patient-centered care allowed us to effectively collaborate to bring the patients goals of care to the forefront aligning patients, families, physicians, nurses, and staff during the COVID-19 surge.

Dr. Johnston is associate professor at Dell Medical School at The University of Texas in Austin. She practices hospital medicine and inpatient palliative care at Dell Seton Medical Center. Dr. Cooremans is a resident physician at Dell Medical School. Dr. Salib is the internal medicine clerkship director and an associate professor at Dell Medical School. Dr. Nieto is an assistant professor and associate chief of the Division of Hospital Medicine at Dell Medical School. Dr. Patel is an assistant professor at Dell Medical School. This article is part of a series written by members of the Division of Hospital Medicine at Dell Medical School, exploring lessons learned from the coronavirus pandemic and outlining an approach for creating COVID-19 Centers of Excellence. The article first appeared in The Hospital Leader, the official blog of SHM.

Patients dying without their loved ones, families forced to remotely decide goals of care without the physical presence or human connection of the care team, overworked staff physically isolated from their critically ill patients, and at-risk community members with uncertain and undocumented goals for care are among the universal challenges confronted by hospitals and hospitalists during this COVID-19 pandemic. Partnerships among hospital medicine (HM) and palliative care (PC) teams at Dell Medical School/Dell Seton Medical Center thrive on mutually shared core values of patient centered care – compassion, empathy, and humanity.

A key PC-HM collaboration was adapting our multidisciplinary huddle to focus on communication effectiveness and efficiency in the medical intensive care unit (MICU). Expanded interprofessional and cross-specialty collaboration promoted streamlined, succinct, and standardized communication with patients’ families while their loved ones were critically ill with COVID-19. The PC team attended daily MICU multidisciplinary huddles, attentive to both the medical and psychosocial updates for each patient. During huddles, residents or HM providers were asked to end their presentation with a clinical status “headline” and solicited feedback from the multidisciplinary team before messaging to the family. The PC team then communicated with families a succinct and cohesive medical update and continuously explored goals of care. This allowed the HM team, often overwhelmed with admissions, co-managing intensive care patients, and facilitating safe discharges, to focus on urgent issues while PC provided continuity and personalized support for patients and families. PC’s ability to synthesize and summarize clinical information from multiple teams and then provide cohesive updates in patient-friendly language modeled important communication skills for learners and simultaneously benefited HM providers.

Our chaplains, too, were central to facilitating timely, proactive conversations and documentation of Medical Power of Attorney (MPOA) for patients with COVID-19 admitted to our hospital. HM prioritized early admission conversations with patients to counsel them on severity of illness, prognosis based on risk factors, to elucidate wishes for intubation or resuscitation, and to capture their desired medical decision maker. HM was notified of all COVID and PUI admissions, allowing us to speak with even critically ill patients in the ER or ICU prior to intubation in order to quickly and accurately capture patients’ wishes for treatment and delegate decision makers. Our chaplains supported and supplemented these efforts by diligently and dutifully soliciting, hearing, and documenting patient MPOA delegates, with over 50% MPOA completion by 24 hours of hospitalization.

Another early PC-HM project, “Meet My Loved One,” was adapted from the University of Alabama at Birmingham Palliative and Comfort Unit. The absence of families visiting the ICU and sharing pictures, stories, anecdotes of our patients left a deeply felt, dehumanizing void in the halls and rooms of our hospital. To fill this space with life and humanity, furloughed medical students on their “transition of care” electives contacted family members of their “continuity” patients focusing primarily on those patients expected to have prolonged ICU or hospital stays and solicited personal, humanizing information about our patients. Questions included: “What is your loved one’s preferred name or nickname?” and “What are three things we should know to take better care of your loved one?” With family permission, we posted this information on the door outside the patient’s room. Nursing staff, in particular, appreciated getting to know their patients more personally and families appreciated the staff’s desire to know their loved one as an individual.

It is also important to acknowledge setbacks. Early efforts to engage technology proved more foe than friend. We continue to struggle with using our iPads for video visits. Most of our families prefer “WhatsApp” for video communication, which is not compatible with operating systems on early versions of the iPad, which were generously and widely donated by local school systems. Desperate to allow families to connect, many providers resorted to using personal devices to facilitate video visits and family meetings. And we discovered that many video visits caused more not less family angst, especially for critically ill patients. Families often required preparation and coaching on what to expect and how to interact with intubated, sedated, proned, and paralyzed loved ones.

Our hospital medicine and palliative care teams have an established strong partnership. The COVID-19 pandemic created novel communication challenges but our shared mission toward patient-centered care allowed us to effectively collaborate to bring the patients goals of care to the forefront aligning patients, families, physicians, nurses, and staff during the COVID-19 surge.

Dr. Johnston is associate professor at Dell Medical School at The University of Texas in Austin. She practices hospital medicine and inpatient palliative care at Dell Seton Medical Center. Dr. Cooremans is a resident physician at Dell Medical School. Dr. Salib is the internal medicine clerkship director and an associate professor at Dell Medical School. Dr. Nieto is an assistant professor and associate chief of the Division of Hospital Medicine at Dell Medical School. Dr. Patel is an assistant professor at Dell Medical School. This article is part of a series written by members of the Division of Hospital Medicine at Dell Medical School, exploring lessons learned from the coronavirus pandemic and outlining an approach for creating COVID-19 Centers of Excellence. The article first appeared in The Hospital Leader, the official blog of SHM.

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