Clinical Edge

Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions

NSAID/triptan combination improves treatment-resistant migraine

Key clinical point: The NSAID/triptan combination could be best suited for patients who have failed acute treatments.

Major finding: The combination outperformed rizatriptan alone with respect to 1-hour pain relief (44% vs. 37%) and 2- to 24-hour sustained pain relief (53% vs. 44%).

Study details: Randomized, controlled trial (n = 1,594).

Disclosures: The study was funded by Axsome Therapeutics. Dr. O’Gorman is an employee of Axsome.

Citation:

O’Gorman C et al. AHS 2020, Abstract 840673.